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Organic & Biomolecular Chemistry|July 31, 2026
4-Dehydroxymethyl-4-C-biphenyl-DAB derivatives: introduction of a biphenyl group at the C4 position shifts the binding selectivity, resulting in improved affinity for lysosomal acid β-glucocerebrosidaseKosuke Yoshimura, Izumi Nakagome, Yi-Xian Li, et al.
European Journal of Medicinal Chemistry|January 5, 2023
Nanomolar β-glucosidase and β-galactosidase inhibition by enantiomeric α-1-C-alkyl-1,4-dideoxy-1,4-imino-arabinitol derivativesDong Zi, Ying-Ying Song, Tian-Tian Lu, et al.
European Journal of Medicinal Chemistry|August 20, 2024
Design, synthesis and structure-activity relationship of novel 2-pyrimidinylindole derivatives as orally available anti-obesity agentsLi-Yuan Wei, Yu-Wei Lin, Jia-Chun Luo, et al.
Organic & Biomolecular Chemistry|July 15, 2022
Introduction of C-alkyl branches to L-iminosugars changes their active site binding orientationAtsushi Kato, Izumi Nakagome, Kosuke Yoshimura, et al.
European Journal of Medicinal Chemistry|June 15, 2024
Design and synthesis of 6-C-alkyl-DMDP type nanomolar inhibitors of β-galactosidase and β-glucosidase based on broussonetine S and related derivativesFeng-Teng Gao, Qing-Kun Wu, Ming Zhang, et al.
Systematic Biology|July 31, 2025
Species Diversification in the Sky Islands of Southwestern China Revealed by Genomic, Introgression and Demographic Analyses of Asian Shrew MolesYi-Xian Li, Zhong-Zheng Chen, Quan Li, et al.
Molecular Phylogenetics and Evolution|June 11, 2026
Integrative taxonomic revision of Uropsilus (Uropsilinae, Talpidae) combining genomic, morphological and geographic evidenceYi-Xian Li, Quan Li, Wen-Yu Song, et al.
Journal of Medicinal Chemistry|January 24, 2022
5-C-Branched Deoxynojirimycin: Strategy for Designing a 1-Deoxynojirimycin-Based Pharmacological Chaperone with a Nanomolar Affinity for Pompe DiseaseAtsushi Kato, Izumi Nakagome, Uta Kanekiyo, et al.
Frontiers in Microbiology|July 15, 2025
Screening of host proteins interacting with the African swine fever virus outer membrane protein CD2vXiong-Nan Chen, Gao-Xi Zhu, Yi-Xian Li, et al.
Journal of Medicinal Chemistry|July 12, 2024
Development of Novel N-Acylhydrazone Derivatives with High Anti-obesity Activity and Improved Safety by Exploring the Pharmaceutical Properties of Aldehyde GroupZhi Jiang, Yu-Tao Hu, Shi-Yao Guo, et al.
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