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Molecular Cell|February 14, 2012
OTUB1 co-opts Lys48-linked ubiquitin recognition to suppress E2 enzyme functionYu-Chi Juang, Marie-Claude Landry, Mario Sanches, et al.
Molecular Cell|January 18, 2016
HELB Is a Feedback Inhibitor of DNA End ResectionJán Tkáč, Guotai Xu, Hemanta Adhikary, et al.
Molecular Systems Biology|May 30, 2018
Mapping DNA damage-dependent genetic interactions in yeast via party mating and barcode fusion geneticsJ Javier Díaz-Mejía, Albi Celaj, Joseph C Mellor, et al.
Nature Chemical Biology|April 9, 2026
The molecular glue CLEO4-88 inhibits the ACAA1 thiolase by induced binding to GID4Chetan K Chana, Ines Ben Makhlouf, Jaeyoun Kim, et al.
Science Translational Medicine|January 29, 2011
Uroporphyrinogen decarboxylase is a radiosensitizing target for head and neck cancerEmma Ito, Shijun Yue, Eduardo H Moriyama, et al.
Cell|February 11, 2009
The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damageGrant S Stewart, Stephanie Panier, Kelly Townsend, et al.
The Journal of Pathology|June 20, 2020
SMARCB1 loss induces druggable cyclin D1 deficiency via upregulation of MIR17HG in atypical teratoid rhabdoid tumorsYibo Xue, Xianbing Zhu, Brian Meehan, et al.
Nature Communications|August 29, 2014
Structure and mechanism of action of the hydroxy-aryl-aldehyde class of IRE1 endoribonuclease inhibitorsMario Sanches, Nicole M Duffy, Manisha Talukdar, et al.
Molecular Cell|June 10, 2020
Endogenous DNA 3' Blocks Are Vulnerabilities for BRCA1 and BRCA2 Deficiency and Are Reversed by the APE2 NucleaseAlejandro Álvarez-Quilón, Jessica L Wojtaszek, Marie-Claude Mathieu, et al.
Nature|July 6, 2018
CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesionsMichal Zimmermann, Olga Murina, Martin A M Reijns, et al.
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