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Cell|June 21, 2011
An allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzymeDerek F Ceccarelli, Xiaojing Tang, Benoit Pelletier, et al.
Molecular Systems Biology|April 5, 2024
Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stabilityYiQing Lü, Tiffany Cho, Saptaparna Mukherjee, et al.
Nature|November 25, 2021
FAM72A antagonizes UNG2 to promote mutagenic repair during antibody maturationYuqing Feng, Conglei Li, Jessica A Stewart, et al.
Nature Biotechnology|November 28, 2017
Inhibition of 53BP1 favors homology-dependent DNA repair and increases CRISPR-Cas9 genome-editing efficiencyMarella D Canny, Nathalie Moatti, Leo C K Wan, et al.
Nature Communications|November 25, 2025
WEE1 inhibitors trigger GCN2-mediated activation of the integrated stress responseRinskje B Tjeerdsma, Timothy F Ng, Maurits Roorda, et al.
Cancer Research|January 26, 2024
Cotargeting CDK4/6 and BRD4 Promotes Senescence and Ferroptosis Sensitivity in CancerXianbing Zhu, Zheng Fu, Kendall Dutchak, et al.
Molecular Cell|November 9, 2010
The MMS22L-TONSL complex mediates recovery from replication stress and homologous recombinationLara O'Donnell, Stephanie Panier, Jan Wildenhain, et al.
Nature Chemical Biology|August 12, 2020
Functional characterization of a PROTAC directed against BRAF mutant V600EGanna Posternak, Xiaojing Tang, Pierre Maisonneuve, et al.
G3 (Bethesda, Md.)|June 29, 2017
Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout ScreensTraver Hart, Amy Hin Yan Tong, Katie Chan, et al.
Nature Communications|September 14, 2021
SMARCA4/2 loss inhibits chemotherapy-induced apoptosis by restricting IP3R3-mediated Ca2+ flux to mitochondriaYibo Xue, Jordan L Morris, Kangning Yang, et al.
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