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Molecular Pharmacology|June 28, 2019
Identification of Abundant and Evolutionarily Conserved Opioid Receptor Circular RNAs in the Nervous System Modulated by MorphineTakeshi Irie, Rebecca Shum, Ioanna Deni, et al.
International Journal of Molecular Sciences|March 25, 2022
Exploring Pharmacological Functions of Alternatively Spliced Variants of the Mu Opioid Receptor Gene, Oprm1, via Gene-Targeted Animal ModelsWenjian Kang, Shan Liu, Jin Xu, et al.
Proceedings of the National Academy of Sciences of the United States of America|March 16, 2016
Truncated mu opioid GPCR variant involvement in opioid-dependent and opioid-independent pain modulatory systems within the CNSGina F Marrone, Steven G Grinnell, Zhigang Lu, et al.
ACS Chemical Neuroscience|September 21, 2016
Tetrapeptide Endomorphin Analogs Require Both Full Length and Truncated Splice Variants of the Mu Opioid Receptor Gene Oprm1 for AnalgesiaGina F Marrone, Zhigang Lu, Grace Rossi, et al.
Neuropharmacology|February 2, 2023
Binding preference at the μ-opioid receptor underlies distinct pharmacology of cyclopropyl versus valeryl analogs of fentanylBing Xie, Valerie P Le Rouzic, Alexander Goldberg, et al.
Neuropharmacology|August 16, 2017
Pharmacological characterization of novel synthetic opioids (NSO) found in the recreational drug marketplaceMichael H Baumann, Susruta Majumdar, Valerie Le Rouzic, et al.
JCI Insight|December 5, 2017
Fentanyl-related designer drugs W-18 and W-15 lack appreciable opioid activity in vitro and in vivoXi-Ping Huang, Tao Che, Thomas J Mangano, et al.
Molecular Pharmacology|March 8, 2026
Differential impacts of exon 1-associated and exon 11-associated variants of the rat mu opioid receptor gene, Oprm1, on buprenorphine- and morphine-induced analgesia and respiratory depression in male ratsTiffany Zhang, Jin Xu, Valerie P Le Rouzic, et al.
Journal of Medicinal Chemistry|June 28, 2012
Synthesis and evaluation of aryl-naloxamide opiate analgesics targeting truncated exon 11-associated μ opioid receptor (MOR-1) splice variantsSusruta Majumdar, Joan Subrath, Valerie Le Rouzic, et al.
Synapse (New York, N.Y.)|May 26, 2016
Mediation of buprenorphine analgesia by a combination of traditional and truncated mu opioid receptor splice variantsSteven G Grinnell, Michael Ansonoff, Gina F Marrone, et al.
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