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Journal of Medicinal Chemistry|April 9, 2026
From KRAS<sup><i>G12D</i></sup> to Pan-KRAS Inhibitors─A Journey Enabled by Synthetic Innovation and Structure-Based Drug DesignXiaoshen Ma, David L Sloman, Timothy J Henderson, et al.Journal of Medicinal Chemistry|March 23, 2021
The Discovery of Two Novel Classes of 5,5-Bicyclic Nucleoside-Derived PRMT5 Inhibitors for the Treatment of CancerRyan V Quiroz, Michael H Reutershan, Sebastian E Schneider, et al.Lancet (London, England)|May 20, 2020
Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trialYeming Wang, Dingyu Zhang, Guanhua Du, et al.Journal of Medicinal Chemistry|November 11, 2011
Discovery of a potent and orally bioavailable benzolactam-derived inhibitor of Polo-like kinase 1 (MLN0905)Matthew O Duffey, Tricia J Vos, Ruth Adams, et al.Pageof 6