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The AAPS Journal|September 12, 2023
Ensemble Machine Learning Approaches Based on Molecular Descriptors and Graph Convolutional Networks for Predicting the Efflux Activities of MDR1 and BCRP TransportersAsahi Adachi, Tomoki Yamashita, Shigehiko Kanaya, et al.Journal of Pharmaceutical and Biomedical Analysis|May 31, 2022
Highly-sensitive simultaneous quantitation of glucosylsphingosine and galactosylsphingosine in human cerebrospinal fluid by liquid chromatography/tandem mass spectrometryShin-Ichi Matsumoto, Sho Sato, Kentaro Otake, et al.The AAPS Journal|May 19, 2021
Direct Comparison of the Prediction of the Unbound Brain-to-Plasma Partitioning Utilizing Machine Learning Approach and Mechanistic Neuropharmacokinetic ModelYohei Kosugi, Kunihiko Mizuno, Cipriano Santos, et al.Xenobiotica; the Fate of Foreign Compounds in Biological Systems|October 1, 2013
Risk assessment of drug-drug interactions using hepatocytes suspended in serum during the drug discovery processYohei Kosugi, Hideki Hirabayashi, Tomoko Igari, et al.Drug Metabolism and Pharmacokinetics|April 10, 2026
Advances in In silico predictive models for DDI prediction: Implications and practical applications in drug discoveryKoichi Handa, Hideaki Mamada, Shinji Nakayama, et al.Xenobiotica; the Fate of Foreign Compounds in Biological Systems|August 12, 2020
Characterization of plasma protein binding in two mouse models of humanized liver, PXB mouse and humanized TK-NOG mouseMaki Miyamoto, Yohei Kosugi, Shinji Iwasaki, et al.Xenobiotica; the Fate of Foreign Compounds in Biological Systems|November 29, 2011
Evaluation of cytochrome P450-mediated drug-drug interactions based on the strategies recommended by regulatory authoritiesYohei Kosugi, Hideki Hirabayashi, Tomoko Igari, et al.Xenobiotica; the Fate of Foreign Compounds in Biological Systems|February 13, 2019
Prediction of human pharmacokinetics of long half-life compounds using chimeric mice with humanised liverMaki Miyamoto, Shinji Iwasaki, Ikumi Chisaki, et al.Journal of Pharmaceutical Sciences|February 28, 2015
Evaluation of Acid Tolerance of Drugs Using Rats and Dogs Controlled for Gastric Acid SecretionYohei Kosugi, Syunsuke Yamamoto, Noriyasu Sano, et al.Frontiers in Neurology|November 14, 2025
Characterization of a humanized mouse model of Charcot-Marie-Tooth type 1A for the discovery of human PMP22-targeting drugsAtsuki Taruta, Shin-Ichi Matsumoto, Yasushi Masuda, et al.Pageof 4