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Journal of Medicinal Chemistry|March 8, 2021
Discovery of a Potent and Orally Bioavailable Melatonin Receptor AgonistYasutaka Hoashi, Takafumi Takai, Yohei Kosugi, et al.Molecular Pharmaceutics|April 19, 2005
Involvement of OCTN1 (SLC22A4) in pH-dependent transport of organic cationsIkumi Tamai, Takeo Nakanishi, Daisuke Kobayashi, et al.Journal of Medicinal Chemistry|May 17, 2011
Synthesis of a novel series of tricyclic dihydrofuran derivatives: discovery of 8,9-dihydrofuro[3,2-c]pyrazolo[1,5-a]pyridines as melatonin receptor (MT1/MT2) ligandsTatsuki Koike, Takafumi Takai, Yasutaka Hoashi, et al.Journal of Medicinal Chemistry|January 6, 2021
Discovery of a Novel and Brain-Penetrant O-GlcNAcase Inhibitor via Virtual Screening, Structure-Based Analysis, and Rational Lead OptimizationMichiko Tawada, Makoto Fushimi, Kei Masuda, et al.The Journal of Obstetrics and Gynaecology Research|September 10, 2022
Quantitative assessment of coat-hanger ribs detected on three-dimensional ultrasound for prenatal diagnosis of Kagami-Ogata syndromeAkane Kuriki, Satoshi Hosoya, Katsusuke Ozawa, et al.Pharmaceutical Research|April 3, 2019
Direct Drug Delivery of Low-Permeable Compounds to the Central Nervous System Via Intranasal Administration in Rats and MonkeysShinji Iwasaki, Syunsuke Yamamoto, Noriyasu Sano, et al.Xenobiotica; the Fate of Foreign Compounds in Biological Systems|December 6, 2018
Application of unbound liver-to-plasma concentration ratio to quantitative projection of cytochrome P450-mediated drug-drug interactions using physiologically based pharmacokinetic modelling approachShinji Iwasaki, Yohei Kosugi, Andy Z X Zhu, et al.Bioorganic & Medicinal Chemistry|January 21, 2014
Design, synthesis, and biological evaluation of a series of piperazine ureas as fatty acid amide hydrolase inhibitorsMitsunori Kono, Takahiro Matsumoto, Toshihiro Imaeda, et al.Scientific Reports|July 16, 2021
Strictly regulated agonist-dependent activation of AMPA-R is the key characteristic of TAK-653 for robust synaptic responses and cognitive improvementAtsushi Suzuki, Akiyoshi Kunugi, Yasukazu Tajima, et al.Bioorganic & Medicinal Chemistry|February 9, 2017
Discovery of 4-chloro-2-(2,4-dichloro-6-methylphenoxy)-1-methyl-7-(pentan-3-yl)-1H-benzimidazole, a novel CRF1 receptor antagonistMichiyo Mochizuki, Takuto Kojima, Katsumi Kobayashi, et al.Pageof 4