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Biological & Pharmaceutical Bulletin|March 5, 2019
Utility of Chimeric Mice with Humanized Liver for Predicting Human Pharmacokinetics in Drug Discovery: Comparison with in Vitro-in Vivo Extrapolation and Allometric ScalingYoichi Naritomi, Seigo Sanoh, Shigeru Ohta
Drug Metabolism and Pharmacokinetics|November 30, 2017
Chimeric mice with humanized liver: Application in drug metabolism and pharmacokinetics studies for drug discoveryYoichi Naritomi, Seigo Sanoh, Shigeru Ohta
Drug Metabolism and Pharmacokinetics|October 23, 2004
Utility of microtiter plate assays for human cytochrome P450 inhibition studies in drug discovery: application of simple method for detecting quasi-irreversible and irreversible inhibitorsYoichi Naritomi, Yuriko Teramura, Shigeyuki Terashita, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|April 16, 2003
Utility of hepatocytes in predicting drug metabolism: comparison of hepatic intrinsic clearance in rats and humans in vivo and in vitroYoichi Naritomi, Shigeyuki Terashita, Akira Kagayama, et al.
Drug Metabolism and Pharmacokinetics|March 12, 2015
Prediction of hepatic and intestinal glucuronidation using in vitro-in vivo extrapolationYoichi Naritomi, Fumihiro Nakamori, Takako Furukawa, et al.
Drug Metabolism and Pharmacokinetics|October 27, 2011
A practical and direct comparison of intrinsic metabolic clearance of several non-CYP enzyme substrates in freshly isolated and cryopreserved hepatocytesTakafumi Akabane, Nicolas Gerst, Yoichi Naritomi, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|December 17, 2013
Comparison of intestinal metabolism of CYP3A substrates between rats and humans: application of portal-systemic concentration difference methodKeitaro Kadono, Akiko Koakutsu, Yoichi Naritomi, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|May 1, 2012
Method for predicting human intestinal first-pass metabolism of UGT substrate compoundsTakako Furukawa, Katsuhiro Yamano, Yoichi Naritomi, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|May 14, 2020
Predictability of human pharmacokinetics of drugs that undergo hepatic organic anion transporting polypeptide (OATP)-mediated transport using single-species allometric scaling in chimeric mice with humanized liver: integration with hepatic drug metabolismSeigo Sanoh, Yoichi Naritomi, Satoshi Kitamura, et al.
Drug Metabolism and Pharmacokinetics|October 6, 2011
Quantitative prediction of intestinal glucuronidation of drugs in rats using in vitro metabolic clearance dataTakako Furukawa, Fumihiro Nakamori, Kazuhiro Tetsuka, et al.
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