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Life Science Alliance|May 15, 2023
The C-type lectin domain of CD62P (P-selectin) functions as an integrin ligandYoko K Takada, Scott I Simon, Yoshikazu TakadaInternational Journal of Molecular Sciences|November 13, 2025
PF4 Autoantibody Complexes Cause Activation of Integrins αIIbβ3 and αvβ3 and Possible Subsequent Thrombosis and Autoimmune DiseasesYoko K Takada, Chun-Yi Wu, Yoshikazu TakadaInternational Journal of Molecular Sciences|May 13, 2026
IGF1 Binding to Integrin αvβ3 Induces Direct Gα13 Binding to IGF1R KinaseYoko K Takada, Chun-Yi Wu, Yoshikazu TakadaThe Biochemical Journal|January 6, 2018
Stromal cell-derived factor-1 (CXCL12) activates integrins by direct binding to an allosteric ligand-binding site (site 2) of integrins without CXCR4Masaaki Fujita, Parastoo Davari, Yoko K Takada, et al.Biorxiv : the Preprint Server for Biology|February 12, 2026
Galectin-3 binds to the RGD-binding site in a glycan-independent manner and to the allosteric site and activates integrins αvβ3, αIIbβ3, and α5β1Yoko K Takada, Yu-Jui Yvonne Wan, Yoshikazu TakadaPlos One|April 4, 2014
The binding of monomeric C-reactive protein (mCRP) to Integrins αvβ3 and α4β1 is related to its pro-inflammatory actionMasaaki Fujita, Yoko K Takada, Yoshihiro Izumiya, et al.Journal of Immunology (Baltimore, Md. : 1950)|July 24, 2019
Integrin Binding to the Trimeric Interface of CD40L Plays a Critical Role in CD40/CD40L SignalingYoko K Takada, Jessica Yu, Michiko Shimoda, et al.Biomolecules|May 4, 2026
Galectin-3 Binds to the Allosteric Site and Activates Integrins αvβ3, αIIbβ3, and α5β1, and Lactose Inhibits This ActivationYoko K Takada, Yu-Jui Yvonne Wan, Yoshikazu TakadaBiomolecules|August 29, 2024
FGF1 Suppresses Allosteric Activation of β3 Integrins by FGF2: A Potential Mechanism of Anti-Inflammatory and Anti-Thrombotic Action of FGF1Yoko K Takada, Xuesong Wu, David Wei, et al.The Journal of Biological Chemistry|October 15, 2017
Direct binding to integrins and loss of disulfide linkage in interleukin-1β (IL-1β) are involved in the agonistic action of IL-1βYoko K Takada, Jessica Yu, Masaaki Fujita, et al.Pageof 4