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Yongxin Han

Showing results (41-50 of 68) with videos related to

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Bioorganic & Medicinal Chemistry Letters|July 26, 2011
Impact of passive permeability and gut efflux transport on the oral bioavailability of novel series of piperidine-based renin inhibitors in rodentsJean-François Lévesque, Kelly Bleasby, Amandine Chefson, et al.
Bioorganic & Medicinal Chemistry Letters|February 23, 2008
Structure-activity relationships and pharmacokinetic parameters of quinoline acylsulfonamides as potent and selective antagonists of the EP(4) receptorJason D Burch, Michel Belley, Réjean Fortin, et al.
Journal of Medicinal Chemistry|February 19, 2010
The discovery of 4-{1-[({2,5-dimethyl-4-[4-(trifluoromethyl)benzyl]-3-thienyl}carbonyl)amino]cyclopropyl}benzoic acid (MK-2894), a potent and selective prostaglandin E2 subtype 4 receptor antagonistMarc Blouin, Yongxin Han, Jason Burch, et al.
Cancer Discovery|April 8, 2024
The Pan-RAF-MEK Nondegrading Molecular Glue NST-628 Is a Potent and Brain-Penetrant Inhibitor of the RAS-MAPK Pathway with Activity across Diverse RAS- and RAF-Driven CancersMeagan B Ryan, Bradley Quade, Natasha Schenk, et al.
Bioorganic & Medicinal Chemistry Letters|February 14, 2012
3,4-Diarylpiperidines as potent renin inhibitorsPatrick Lacombe, Mélissa Arbour, Renée Aspiotis, et al.
Bioorganic & Medicinal Chemistry Letters|August 29, 2009
Design, synthesis, and evaluation of novel 3-amino-4-hydrazine-cyclobut-3-ene-1,2-diones as potent and selective CXCR2 chemokine receptor antagonistsShilan Liu, Yinhui Liu, Hongmei Wang, et al.
Bioorganic & Medicinal Chemistry Letters|July 19, 2005
Lipophilic versus hydrogen-bonding effect in P3 on potency and selectivity of valine aspartyl ketones as caspase 3 inhibitorsChristophe Mellon, Reneé Aspiotis, Cameron W Black, et al.
Bioorganic & Medicinal Chemistry Letters|January 26, 2007
Solid-phase analogue synthesis of caspase-3 inhibitors via palladium-catalyzed amination of 3-bromopyrazinonesElise Isabel, Renee Aspiotis, W Cameron Black, et al.
Bioorganic & Medicinal Chemistry Letters|March 28, 2012
Design and synthesis of potent, isoxazole-containing renin inhibitorsPierre-André Fournier, Mélissa Arbour, Elizabeth Cauchon, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of Disubstituted Imidazo[4,5-b]pyridines and Purines as Potent TrkA InhibitorsTao Wang, Michelle L Lamb, Michael H Block, et al.
Pageof 7

Showing results (41-50 of 68) with videos related to

Sort By:
Pageof 7
Bioorganic & Medicinal Chemistry Letters|July 26, 2011
Impact of passive permeability and gut efflux transport on the oral bioavailability of novel series of piperidine-based renin inhibitors in rodentsJean-François Lévesque, Kelly Bleasby, Amandine Chefson, et al.
Bioorganic & Medicinal Chemistry Letters|February 23, 2008
Structure-activity relationships and pharmacokinetic parameters of quinoline acylsulfonamides as potent and selective antagonists of the EP(4) receptorJason D Burch, Michel Belley, Réjean Fortin, et al.
Journal of Medicinal Chemistry|February 19, 2010
The discovery of 4-{1-[({2,5-dimethyl-4-[4-(trifluoromethyl)benzyl]-3-thienyl}carbonyl)amino]cyclopropyl}benzoic acid (MK-2894), a potent and selective prostaglandin E2 subtype 4 receptor antagonistMarc Blouin, Yongxin Han, Jason Burch, et al.
Cancer Discovery|April 8, 2024
The Pan-RAF-MEK Nondegrading Molecular Glue NST-628 Is a Potent and Brain-Penetrant Inhibitor of the RAS-MAPK Pathway with Activity across Diverse RAS- and RAF-Driven CancersMeagan B Ryan, Bradley Quade, Natasha Schenk, et al.
Bioorganic & Medicinal Chemistry Letters|February 14, 2012
3,4-Diarylpiperidines as potent renin inhibitorsPatrick Lacombe, Mélissa Arbour, Renée Aspiotis, et al.
Bioorganic & Medicinal Chemistry Letters|August 29, 2009
Design, synthesis, and evaluation of novel 3-amino-4-hydrazine-cyclobut-3-ene-1,2-diones as potent and selective CXCR2 chemokine receptor antagonistsShilan Liu, Yinhui Liu, Hongmei Wang, et al.
Bioorganic & Medicinal Chemistry Letters|July 19, 2005
Lipophilic versus hydrogen-bonding effect in P3 on potency and selectivity of valine aspartyl ketones as caspase 3 inhibitorsChristophe Mellon, Reneé Aspiotis, Cameron W Black, et al.
Bioorganic & Medicinal Chemistry Letters|January 26, 2007
Solid-phase analogue synthesis of caspase-3 inhibitors via palladium-catalyzed amination of 3-bromopyrazinonesElise Isabel, Renee Aspiotis, W Cameron Black, et al.
Bioorganic & Medicinal Chemistry Letters|March 28, 2012
Design and synthesis of potent, isoxazole-containing renin inhibitorsPierre-André Fournier, Mélissa Arbour, Elizabeth Cauchon, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of Disubstituted Imidazo[4,5-b]pyridines and Purines as Potent TrkA InhibitorsTao Wang, Michelle L Lamb, Michael H Block, et al.
Pageof 7