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Chembiochem : a European Journal of Chemical Biology|September 14, 2011
Enhancing the thermal robustness of an enzyme by directed evolution: least favorable starting points and inferior mutants can map superior evolutionary pathwaysYosephine Gumulya, Manfred T Reetz
The Biochemical Journal|December 24, 2016
Exploring the past and the future of protein evolution with ancestral sequence reconstruction: the 'retro' approach to protein engineeringYosephine Gumulya, Elizabeth M J Gillam
Chembiochem : a European Journal of Chemical Biology|April 24, 2012
Many pathways in laboratory evolution can lead to improved enzymes: how to escape from local minimaYosephine Gumulya, Joaquin Sanchis, Manfred T Reetz
Journal of Computer-Aided Molecular Design|December 14, 2017
Learning epistatic interactions from sequence-activity data to predict enantioselectivityJulian Zaugg, Yosephine Gumulya, Alpeshkumar K Malde, et al.
Methods in Molecular Biology (Clifton, N.J.)|July 25, 2014
Computational tools for directed evolution: a comparison of prospective and retrospective strategiesJulian Zaugg, Yosephine Gumulya, Elizabeth M J Gillam, et al.
Journal of the American Chemical Society|June 12, 2010
Iterative saturation mutagenesis accelerates laboratory evolution of enzyme stereoselectivity: rigorous comparison with traditional methodsManfred T Reetz, Shreenath Prasad, José D Carballeira, et al.
Journal of Chemical Information and Modeling|February 10, 2018
Effect of Binding on Enantioselectivity of Epoxide HydrolaseJulian Zaugg, Yosephine Gumulya, Mikael Bodén, et al.
Chemical Communications (Cambridge, England)|October 20, 2010
Increasing the stability of an enzyme toward hostile organic solvents by directed evolution based on iterative saturation mutagenesis using the B-FIT methodManfred T Reetz, Pankaj Soni, Layla Fernández, et al.
Nature|November 30, 2017
Genetically programmed chiral organoborane synthesisS B Jennifer Kan, Xiongyi Huang, Yosephine Gumulya, et al.
Microorganisms|December 24, 2021
Potential of Acidithiobacillus ferrooxidans to Grow on and Bioleach Metals from Mars and Lunar Regolith Simulants under Simulated Microgravity ConditionsAnna H Kaksonen, Xiao Deng, Christina Morris, et al.
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