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Current Opinion in Drug Discovery & Development
|
September 9, 2009
Direct small-molecule kinase activation: Novel approaches for a new era of drug discovery
Graham L Simpson, Jennifer A Hughes, Yoshiaki Washio, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 28, 2003
Anilinopyrazole as selective CDK2 inhibitors: design, synthesis, biological evaluation, and X-ray crystallographic analysis
Jun Tang, Lisa M Shewchuk, Hideyuki Sato, et al.
ACS Medicinal Chemistry Letters
|
October 24, 2017
From PIM1 to PI3Kδ via GSK3β: Target Hopping through the Kinome
Zoë A Henley, Benjamin D Bax, Laura M Inglesby, et al.
Chemmedchem
|
June 18, 2019
The Design of Potent, Selective and Drug-Like RGD αvβ1 Small-Molecule Inhibitors Derived from non-RGD α4β1 Antagonists
Richard J D Hatley, Tim N Barrett, Robert J Slack, et al.
Journal of Medicinal Chemistry
|
August 7, 2007
Discovery of novel benzimidazoles as potent inhibitors of TIE-2 and VEGFR-2 tyrosine kinase receptors
Masaichi Hasegawa, Naohiko Nishigaki, Yoshiaki Washio, et al.
Journal of Medicinal Chemistry
|
September 21, 2020
A Turing Test for Molecular Generators
Jacob T Bush, Peter Pogany, Stephen D Pickett, et al.
Journal of Computer-Aided Molecular Design
|
February 28, 2014
Structure-guided optimization of small molecule c-Abl activators
Xuan Hong, Ping Cao, Yoshiaki Washio, et al.
Journal of Medicinal Chemistry
|
February 20, 2020
DNA-Encoded Library Technology-Based Discovery, Lead Optimization, and Prodrug Strategy toward Structurally Unique Indoleamine 2,3-Dioxygenase-1 (IDO1) Inhibitors
Wieslaw M Kazmierski, Bing Xia, John Miller, et al.
Journal of Medicinal Chemistry
|
January 29, 2019
Identification and Optimization of Novel Small c-Abl Kinase Activators Using Fragment and HTS Methodologies
Graham L Simpson, Sophie M Bertrand, Jennifer A Borthwick, et al.
Journal of Medicinal Chemistry
|
August 25, 2015
Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3-Kinase δ for the Treatment of Respiratory Disease
Kenneth Down, Augustin Amour, Ian R Baldwin, et al.
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of 2
Search research articles
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Showing results (1-10 of 12) with videos related to
Sort By:
Page
of 2
Current Opinion in Drug Discovery & Development
|
September 9, 2009
Direct small-molecule kinase activation: Novel approaches for a new era of drug discovery
Graham L Simpson, Jennifer A Hughes, Yoshiaki Washio, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 28, 2003
Anilinopyrazole as selective CDK2 inhibitors: design, synthesis, biological evaluation, and X-ray crystallographic analysis
Jun Tang, Lisa M Shewchuk, Hideyuki Sato, et al.
ACS Medicinal Chemistry Letters
|
October 24, 2017
From PIM1 to PI3Kδ via GSK3β: Target Hopping through the Kinome
Zoë A Henley, Benjamin D Bax, Laura M Inglesby, et al.
Chemmedchem
|
June 18, 2019
The Design of Potent, Selective and Drug-Like RGD αvβ1 Small-Molecule Inhibitors Derived from non-RGD α4β1 Antagonists
Richard J D Hatley, Tim N Barrett, Robert J Slack, et al.
Journal of Medicinal Chemistry
|
August 7, 2007
Discovery of novel benzimidazoles as potent inhibitors of TIE-2 and VEGFR-2 tyrosine kinase receptors
Masaichi Hasegawa, Naohiko Nishigaki, Yoshiaki Washio, et al.
Journal of Medicinal Chemistry
|
September 21, 2020
A Turing Test for Molecular Generators
Jacob T Bush, Peter Pogany, Stephen D Pickett, et al.
Journal of Computer-Aided Molecular Design
|
February 28, 2014
Structure-guided optimization of small molecule c-Abl activators
Xuan Hong, Ping Cao, Yoshiaki Washio, et al.
Journal of Medicinal Chemistry
|
February 20, 2020
DNA-Encoded Library Technology-Based Discovery, Lead Optimization, and Prodrug Strategy toward Structurally Unique Indoleamine 2,3-Dioxygenase-1 (IDO1) Inhibitors
Wieslaw M Kazmierski, Bing Xia, John Miller, et al.
Journal of Medicinal Chemistry
|
January 29, 2019
Identification and Optimization of Novel Small c-Abl Kinase Activators Using Fragment and HTS Methodologies
Graham L Simpson, Sophie M Bertrand, Jennifer A Borthwick, et al.
Journal of Medicinal Chemistry
|
August 25, 2015
Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3-Kinase δ for the Treatment of Respiratory Disease
Kenneth Down, Augustin Amour, Ian R Baldwin, et al.
Page
of 2