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Arzneimittel-Forschung|April 23, 2003
Interaction between several medicines and statinsHideki Fujino, Tsuyoshi Saito, Yoshihiko Tsunenari, et al.
Drug Metabolism and Drug Interactions|July 31, 2004
Effect of gemfibrozil on the metabolism of pitavastatin--determining the best animal model for human CYP and UGT activitiesHideki Fujino, Tsuyoshi Saito, Yoshihiko Tsunenari, et al.
Biopharmaceutics & Drug Disposition|December 6, 2018
Pharmacokinetics and metabolism of pemafibrate, a novel selective peroxisome proliferator-activated receptor-alpha modulator, in rats and monkeysShin-Ichiro Ogawa, Yoshihiko Tsunenari, Hiroyuki Kawai, et al.
Bioorganic & Medicinal Chemistry|April 27, 2020
Syntheses and pharmacokinetic evaluations of four metabolites of 2-(4-(2-((1H-benzo[d]imidazol-2-yl)thio)ethyl)piperazin-1-yl)-N-(6-methyl-2,4-bis-(methylthio)pyridin-3-yl)acetamide hydrochloride [K-604], an acyl-CoA:cholesterol O-acyltransferase-1 inhibitorKimiyuki Shibuya, Toru Miura, Tadaaki Ohgiya, et al.
Arzneimittel-Forschung|December 3, 2003
Studies on the interaction between fibrates and statins using human hepatic microsomesHideki Fujino, Syunsuke Shimada, Iwao Yamada, et al.
Drug Metabolism and Drug Interactions|December 20, 2003
Interaction between fibrates and statins--metabolic interactions with gemfibrozilHideki Fujino, Iwao Yamada, Shimada Shimada, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|November 27, 2019
Prediction of circulating human metabolites of pemafibrate, a novel antidyslipidemic drug, using chimeric mice with humanized liverShin-Ichiro Ogawa, Shotaro Uehara, Yoshihiko Tsunenari, et al.
Journal of Medicinal Chemistry|November 16, 2018
Discovery of Clinical Candidate 2-(4-(2-((1 H-Benzo[ d]imidazol-2-yl)thio)ethyl)piperazin-1-yl)- N-(6-methyl-2,4-bis(methylthio)pyridin-3-yl)acetamide Hydrochloride [K-604], an Aqueous-Soluble Acyl-CoA:Cholesterol O-Acyltransferase-1 InhibitorKimiyuki Shibuya, Katsumi Kawamine, Chiyoka Ozaki, et al.
ACS Omega|October 25, 2019
Brain Targeting of Acyl-CoA:Cholesterol O-Acyltransferase-1 Inhibitor K-604 via the Intranasal Route Using a Hydroxycarboxylic Acid SolutionKimiyuki Shibuya, Shigeru Morikawa, Masayoshi Miyamoto, et al.
Bioorganic & Medicinal Chemistry|June 28, 2018
Design, synthesis and pharmacology of aortic-selective acyl-CoA: Cholesterol O-acyltransferase (ACAT/SOAT) inhibitorsKimiyuki Shibuya, Katsumi Kawamine, Toru Miura, et al.
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