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Journal of Pharmaceutical Sciences|April 28, 2012
Long-lasting inhibition of the intestinal absorption of fexofenadine by cyclosporin A in ratsKei Suzuki, Yoshihisa Shitara, Kousuke Fukuda, et al.
The Journal of Pharmacology and Experimental Therapeutics|June 15, 2004
Gemfibrozil and its glucuronide inhibit the organic anion transporting polypeptide 2 (OATP2/OATP1B1:SLC21A6)-mediated hepatic uptake and CYP2C8-mediated metabolism of cerivastatin: analysis of the mechanism of the clinically relevant drug-drug interaction between cerivastatin and gemfibrozilYoshihisa Shitara, Masaru Hirano, Hitoshi Sato, et al.
Toxicology and Applied Pharmacology|August 17, 2010
Multiple mechanisms underlying troglitazone-induced mitochondrial permeability transitionTakuya Okuda, Misaki Norioka, Yoshihisa Shitara, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|April 6, 2006
Drug-drug interaction between pitavastatin and various drugs via OATP1B1Masaru Hirano, Kazuya Maeda, Yoshihisa Shitara, et al.
Cancer Chemotherapy and Pharmacology|February 2, 2010
Zonula Occludens-1 alterations and enhanced intestinal permeability in methotrexate-treated ratsKazuma Hamada, Yoshihisa Shitara, Shuichi Sekine, et al.
European Journal of Drug Metabolism and Pharmacokinetics|August 28, 2015
Pharmacokinetic Herb-Drug Interactions: Insight into Mechanisms and ConsequencesEnoche F Oga, Shuichi Sekine, Yoshihisa Shitara, et al.
The American Journal of Tropical Medicine and Hygiene|July 6, 2012
Potential P-glycoprotein-mediated drug-drug interactions of antimalarial agents in Caco-2 cellsEnoche F Oga, Shuichi Sekine, Yoshihisa Shitara, et al.
Journal of Ethnopharmacology|October 16, 2012
P-glycoprotein mediated efflux in Caco-2 cell monolayers: the influence of herbals on digoxin transportEnoche F Oga, Shuichi Sekine, Yoshihisa Shitara, et al.
Cancer Chemotherapy and Pharmacology|August 22, 2013
Disruption of ZO-1/claudin-4 interaction in relation to inflammatory responses in methotrexate-induced intestinal mucositisKazuma Hamada, Naoko Kakigawa, Shuichi Sekine, et al.
The Journal of Pharmacology and Experimental Therapeutics|November 13, 2008
Physiologically based pharmacokinetic modeling to predict transporter-mediated clearance and distribution of pravastatin in humansTakao Watanabe, Hiroyuki Kusuhara, Kazuya Maeda, et al.
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