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Current Opinion in Chemical Biology|June 21, 2024
Finding ways into the cytosol: Peptide-mediated approaches for delivering proteins into cellsYoshimasa Kawaguchi, Shiroh Futaki
Bioorganic & Medicinal Chemistry|July 25, 2024
An approach for the intracellular delivery of IgG via enzymatic ligation with a cell-permeable attenuated cationic amphiphilic lytic peptideYoshimasa Kawaguchi, Sakahiro Terada, Shiroh Futaki
Chemical & Pharmaceutical Bulletin|September 24, 2025
e3MPH16: A D-Glutamic Acid-Substituted Peptide for Efficient and Low-Cytotoxicity Cytosolic Delivery of MacromoleculesYoshimasa Kawaguchi, Megumi Kiyokawa, Yusei Furuyama, et al.
Bioorganic & Medicinal Chemistry|January 14, 2026
Discovery and characterization of a high-affinity G-quadruplex binding peptide via mRNA displayNaka Kudo Ida, Yoshimasa Kawaguchi, Shiroh Futaki, et al.
The Journal of Physical Chemistry. B|June 1, 2026
A Single L17E Mutation Switches the Membrane Disruption Mechanism of the Spider Venom Peptide M-lycotoxinMiki Ohno, Yoshimasa Kawaguchi, Hisaaki Hirose, et al.
Molecular Pharmaceutics|January 30, 2024
Liquid Droplet-Mediated Formulation of Lipid Nanoparticles Encapsulating Immunoglobulin G for Cytosolic DeliveryYusuke Hirai, Yoshimasa Kawaguchi, Chisato Kasahara, et al.
Angewandte Chemie (International Ed. in English)|November 18, 2025
Microcondensate-Mediated Intracellular Infusion of mRNA Across the Plasma MembraneYoshimasa Kawaguchi, Ayumi Kikkawa, Seigo Kimura, et al.
Bioconjugate Chemistry|July 29, 2025
Membrane Repair Proteins as Negative Regulators of Cytosolic Delivery Using Attenuated Cationic Lytic Peptide L17E and Cell-Penetrating Peptides: Differences and SimilaritiesMasashi Kuriyama, Yoshimasa Kawaguchi, Shinji Ito, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy|January 3, 2025
KCNN4 as a genomic determinant of cytosolic delivery by the attenuated cationic lytic peptide L17EMasashi Kuriyama, Hisaaki Hirose, Yoshimasa Kawaguchi, et al.
Chemical & Pharmaceutical Bulletin|September 24, 2025
A Melittin-Derived Peptide with Improved Cytosolic Delivery Efficiency through Caveolae- and Actin-Mediated EndocytosisYoshimasa Kawaguchi, Naoki Tamemoto, Yusuke Uehata, et al.
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