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Chemical Record (New York, N.Y.)|October 3, 2018
Drug Design Concepts for LSD1-Selective InhibitorsYosuke Ota, Takayoshi Suzuki
Bioorganic & Medicinal Chemistry Letters|December 5, 2017
Histone H3 peptides incorporating modified lysine residues as lysine-specific demethylase 1 inhibitorsTaeko Kakizawa, Yosuke Ota, Yukihiro Itoh, et al.
Molecules (Basel, Switzerland)|May 9, 2018
Design, Synthesis, and In Vitro Evaluation of Novel Histone H3 Peptide-Based LSD1 Inactivators Incorporating α,α-Disubstituted Amino Acids with γ-Turn-Inducing StructuresYosuke Ota, Taeko Kakizawa, Yukihiro Itoh, et al.
Computational and Structural Biotechnology Journal|April 24, 2014
Synthesis, LSD1 Inhibitory Activity, and LSD1 Binding Model of Optically Pure Lysine-PCPA ConjugatesYukihiro Itoh, Daisuke Ogasawara, Yosuke Ota, et al.
Bioorganic & Medicinal Chemistry Letters|April 2, 2015
Histone H3 peptide based LSD1-selective inhibitorsTaeko Kakizawa, Yosuke Ota, Yukihiro Itoh, et al.
Molecular Cancer|February 11, 2010
Bisbenzamidine derivative, pentamidine represses DNA damage response through inhibition of histone H2A acetylationJunya Kobayashi, Akihiro Kato, Yosuke Ota, et al.
Chemical & Pharmaceutical Bulletin|October 30, 2018
Design, Synthesis, and Biological Evaluation of a Conjugate of 5-Fluorouracil and an LSD1 InhibitorYosuke Ota, Arisa Nakamura, Elghareeb E Elboray, et al.
BMC Immunology|July 25, 2024
TLR7 agonist, DSP-0509, with radiation combination therapy enhances anti-tumor activity and modulates T cell dependent immune activationYosuke Ota, Ryosaku Inagaki, Yasuhiro Nagai, et al.
Frontiers in Oncology|September 30, 2024
DSP-0509, a TLR7 agonist, exerted synergistic anti-tumor immunity combined with various immune therapies through modulating diverse immune cells in cancer microenvironmentYosuke Ota, Ryosaku Inagaki, Kentaro Sumida, et al.
Chemical & Pharmaceutical Bulletin|August 2, 2016
False HDAC Inhibition by Aurone CompoundYukihiro Itoh, Miki Suzuki, Taiji Matsui, et al.
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