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Journal of Medicinal Chemistry
|
June 17, 2008
Discovery of novel, potent benzamide inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) exhibiting oral activity in an enzyme inhibition ex vivo model
Lisa D Julian, Zhulun Wang, Tracy Bostick, et al.
ACS Medicinal Chemistry Letters
|
August 23, 2014
Discovery of Potent and Simplified Piperidinone-Based Inhibitors of the MDM2-p53 Interaction
Ming Yu, Yingcai Wang, Jiang Zhu, et al.
Journal of Medicinal Chemistry
|
November 19, 2019
Discovery and in Vivo Evaluation of Macrocyclic Mcl-1 Inhibitors Featuring an α-Hydroxy Phenylacetic Acid Pharmacophore or Bioisostere
Gwenaella Rescourio, Ana Z Gonzalez, Salman Jabri, et al.
Journal of Medicinal Chemistry
|
April 20, 2013
Rational design and binding mode duality of MDM2-p53 inhibitors
Felix Gonzalez-Lopez de Turiso, Daqing Sun, Yosup Rew, et al.
Journal of Medicinal Chemistry
|
October 26, 2025
Discovery of ORIC-533, an Orally Bioavailable CD73 Inhibitor That Maintains Activity in High AMP Environments to Reverse Tumor Immunosuppression
Jared T Moore, Hiroyuki Kawai, Brian R Blank, et al.
Journal of Medicinal Chemistry
|
March 8, 2014
Novel inhibitors of the MDM2-p53 interaction featuring hydrogen bond acceptors as carboxylic acid isosteres
Ana Z Gonzalez, Zhihong Li, Hilary P Beck, et al.
Journal of Medicinal Chemistry
|
April 25, 2012
Structure-based design of novel inhibitors of the MDM2-p53 interaction
Yosup Rew, Daqing Sun, Felix Gonzalez-Lopez De Turiso, et al.
Journal of Medicinal Chemistry
|
November 11, 2014
Discovery of AM-7209, a potent and selective 4-amidobenzoic acid inhibitor of the MDM2-p53 interaction
Yosup Rew, Daqing Sun, Xuelei Yan, et al.
Journal of Medicinal Chemistry
|
February 20, 2014
Selective and potent morpholinone inhibitors of the MDM2-p53 protein-protein interaction
Ana Z Gonzalez, John Eksterowicz, Michael D Bartberger, et al.
Journal of Medicinal Chemistry
|
January 25, 2014
Discovery of AMG 232, a potent, selective, and orally bioavailable MDM2-p53 inhibitor in clinical development
Daqing Sun, Zhihong Li, Yosup Rew, et al.
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Showing results (21-30 of 30) with videos related to
Sort By:
Page
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You have reached the last page of results.
This site can display upto 30 results.
Journal of Medicinal Chemistry
|
June 17, 2008
Discovery of novel, potent benzamide inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) exhibiting oral activity in an enzyme inhibition ex vivo model
Lisa D Julian, Zhulun Wang, Tracy Bostick, et al.
ACS Medicinal Chemistry Letters
|
August 23, 2014
Discovery of Potent and Simplified Piperidinone-Based Inhibitors of the MDM2-p53 Interaction
Ming Yu, Yingcai Wang, Jiang Zhu, et al.
Journal of Medicinal Chemistry
|
November 19, 2019
Discovery and in Vivo Evaluation of Macrocyclic Mcl-1 Inhibitors Featuring an α-Hydroxy Phenylacetic Acid Pharmacophore or Bioisostere
Gwenaella Rescourio, Ana Z Gonzalez, Salman Jabri, et al.
Journal of Medicinal Chemistry
|
April 20, 2013
Rational design and binding mode duality of MDM2-p53 inhibitors
Felix Gonzalez-Lopez de Turiso, Daqing Sun, Yosup Rew, et al.
Journal of Medicinal Chemistry
|
October 26, 2025
Discovery of ORIC-533, an Orally Bioavailable CD73 Inhibitor That Maintains Activity in High AMP Environments to Reverse Tumor Immunosuppression
Jared T Moore, Hiroyuki Kawai, Brian R Blank, et al.
Journal of Medicinal Chemistry
|
March 8, 2014
Novel inhibitors of the MDM2-p53 interaction featuring hydrogen bond acceptors as carboxylic acid isosteres
Ana Z Gonzalez, Zhihong Li, Hilary P Beck, et al.
Journal of Medicinal Chemistry
|
April 25, 2012
Structure-based design of novel inhibitors of the MDM2-p53 interaction
Yosup Rew, Daqing Sun, Felix Gonzalez-Lopez De Turiso, et al.
Journal of Medicinal Chemistry
|
November 11, 2014
Discovery of AM-7209, a potent and selective 4-amidobenzoic acid inhibitor of the MDM2-p53 interaction
Yosup Rew, Daqing Sun, Xuelei Yan, et al.
Journal of Medicinal Chemistry
|
February 20, 2014
Selective and potent morpholinone inhibitors of the MDM2-p53 protein-protein interaction
Ana Z Gonzalez, John Eksterowicz, Michael D Bartberger, et al.
Journal of Medicinal Chemistry
|
January 25, 2014
Discovery of AMG 232, a potent, selective, and orally bioavailable MDM2-p53 inhibitor in clinical development
Daqing Sun, Zhihong Li, Yosup Rew, et al.
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