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Cell Stem Cell|May 22, 2025
HBO1 functions as an epigenetic barrier to hepatocyte plasticity and reprogramming during liver injuryWei-Chien Yuan, Andrew S Earl, Sai Ma, et al.Molecular Therapy : the Journal of the American Society of Gene Therapy|February 5, 2025
Targeting the TRIM21-PD-1 axis potentiates immune checkpoint blockade and CAR-T cell therapyJie Shi, Zijian Zhang, Hsin-Yi Chen, et al.Nature Communications|May 19, 2023
ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapyXiangling Xiao, Jie Shi, Chuan He, et al.Cancer Cell|August 16, 2011
A Cullin3-KLHL20 Ubiquitin ligase-dependent pathway targets PML to potentiate HIF-1 signaling and prostate cancer progressionWei-Chien Yuan, Yu-Ru Lee, Shiu-Feng Huang, et al.Nature Genetics|January 17, 2018
An aberrant SREBP-dependent lipogenic program promotes metastatic prostate cancerMing Chen, Jiangwen Zhang, Katia Sampieri, et al.Science (New York, N.Y.)|May 18, 2019
Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathwayYu-Ru Lee, Ming Chen, Jonathan D Lee, et al.Nature Cell Biology|July 3, 2023
Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammationTao Zhang, Daichao Xu, Jianping Liu, et al.Science (New York, N.Y.)|June 29, 2023
Metabolic orchestration of cell death by AMPK-mediated phosphorylation of RIPK1Tao Zhang, Daichao Xu, Elijah Trefts, et al.Pageof 3