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Journal of Pharmacological Sciences|October 12, 2007
Orally-administered caspase inhibitor PF-03491390 is retained in the liver for prolonged periods with low systemic exposure, exerting a hepatoprotective effect against alpha-fas-induced liver injury in a mouse modelYoshinobu Ueno, Takashi Ohmi, Mitsuko Yamamoto, et al.
The Journal of Pain|March 30, 2025
AK1780, a selective P2X7 receptor antagonist with high central nervous system penetration, exhibits analgesic effect in rat neuropathic pain modelNaomi Shinotsuka, Hirotomo Shimizu, Takayuki Komatsu, et al.
Experimental Eye Research|February 11, 2023
TRPV4 channels promote vascular permeability in retinal vascular diseaseAnri Nishinaka, Miruto Tanaka, Kentaro Ohara, et al.
Bioorganic & Medicinal Chemistry Letters|November 18, 2008
Synthesis and structure-activity relationships of oxamyl dipeptide caspase inhibitors developed for the treatment of liver diseaseHirokazu Ueno, Makoto Kawai, Hirohisa Shimokawa, et al.
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