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Nature Cell Biology|January 16, 2023
Nucleus-exported CLOCK acetylates PRPS to promote de novo nucleotide synthesis and liver tumour growthTong Liu, Zheng Wang, Leiguang Ye, et al.
Nature Cell Biology|May 8, 2023
Creatine kinase B suppresses ferroptosis by phosphorylating GPX4 through a moonlighting functionKe Wu, Meisi Yan, Tong Liu, et al.
Nature Communications|March 16, 2026
INSIG1/2 succination mediated by the moonlighting function of ADSL promotes lipogenesis and liver tumorigenesisYuran Duan, Shuo Wang, Jianyu Liu, et al.
The Journal of Experimental Medicine|March 6, 2025
PCK1 inhibits cGAS-STING activation by consumption of GTP to promote tumor immune evasionWenxing Qin, Yuran Duan, Zhiqiang Hu, et al.
Nature Chemical Biology|January 29, 2025
ADSL promotes autophagy and tumor growth through fumarate-mediated Beclin1 dimethylationLei Wang, Runze Shi, Shuo Wang, et al.
Proceedings of the National Academy of Sciences of the United States of America|January 31, 2025
Transferrin promotes fatty acid oxidation and liver tumor growth through PHD2-mediated PPARα hydroxylation in an iron-dependent mannerXu Qian, Qimin Zhou, Yuan Ouyang, et al.
Nature Chemical Biology|April 25, 2025
PSAT1 impairs ferroptosis and reduces immunotherapy efficacy via GPX4 hydroxylationPeixiang Zheng, Zhiqiang Hu, Yuli Shen, et al.
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