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Bioorganic & Medicinal Chemistry Letters|December 29, 2007
Acylguanidine inhibitors of beta-secretase: optimization of the pyrrole ring substituents extending into the S1 and S3 substrate binding pocketsDerek C Cole, Joseph R Stock, Rajiv Chopra, et al.
Frontiers in Immunology|November 21, 2022
NBTXR3 improves the efficacy of immunoradiotherapy combining nonfucosylated anti-CTLA4 in an anti-PD1 resistant lung cancer modelYun Hu, Sébastien Paris, Genevieve Bertolet, et al.
Bioorganic & Medicinal Chemistry Letters|December 11, 2007
Acylguanidine inhibitors of beta-secretase: optimization of the pyrrole ring substituents extending into the S1' substrate binding pocketLee D Jennings, Derek C Cole, Joseph R Stock, et al.
JCI Insight|June 22, 2023
Nanoparticle-enhanced proton beam immunoradiotherapy drives immune activation and durable tumor rejectionYun Hu, Sébastien Paris, Narayan Sahoo, et al.
Bioorganic & Medicinal Chemistry|May 16, 2009
Synthesis and structure-activity relationship of a novel series of heterocyclic sulfonamide gamma-secretase inhibitorsJun Pu, Anthony F Kreft, Suzan H Aschmies, et al.
Frontiers in Oncology|October 24, 2024
Enhanced tumor control and survival in preclinical models with adoptive cell therapy preceded by low-dose radiotherapyNahum Puebla-Osorio, Natalie Wall Fowlkes, Hampartsoum B Barsoumian, et al.
Bioorganic & Medicinal Chemistry Letters|June 17, 2008
Discovery of a novel series of Notch-sparing gamma-secretase inhibitorsAnthony Kreft, Boyd Harrison, Suzan Aschmies, et al.
Journal of Medicinal Chemistry|October 13, 2006
Acylguanidines as small-molecule beta-secretase inhibitorsDerek C Cole, Eric S Manas, Joseph R Stock, et al.
Molecular Cancer|February 3, 2025
Cancer cells avoid ferroptosis induced by immune cells via fatty acid binding proteinsMaria Angelica Freitas-Cortez, Fatemeh Masrorpour, Hong Jiang, et al.
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