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Molecular and Cellular Biology|March 19, 2008
Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistanceJose R Bayascas, Stephan Wullschleger, Kei Sakamoto, et al.
Nature Communications|March 25, 2023
Neutron-encoded diubiquitins to profile linkage selectivity of deubiquitinating enzymesBianca D M van Tol, Bjorn R van Doodewaerd, Guinevere S M Lageveen-Kammeijer, et al.
EMBO Reports|July 11, 2024
PPTC7 antagonizes mitophagy by promoting BNIP3 and NIX degradation via SCFFBXL4Giang Thanh Nguyen-Dien, Brendan Townsend, Prajakta Gosavi Kulkarni, et al.
Cell Reports|April 12, 2018
Mind Bomb Regulates Cell Death during TNF Signaling by Suppressing RIPK1's Cytotoxic PotentialRebecca Feltham, Kunzah Jamal, Tencho Tenev, et al.
The EMBO Journal|April 7, 2026
Global analysis of cancer cell responses to USP9X inhibitionPhilipp Schenk, Shane M Devine, Simon A Cobbold, et al.
The Journal of Cell Biology|January 28, 2021
The deubiquitylase USP9X controls ribosomal stallingAnne Clancy, Claire Heride, Adán Pinto-Fernández, et al.
Nature Communications|April 15, 2026
GID/CTLH E3 ligase complex control cell fate programs for sexual development of Plasmodium falciparumDanushka S Marapana, Sash Lopaticki, Balu Balan, et al.
Frontiers in Chemistry|May 2, 2022
Insights Into Drug Repurposing, as Well as Specificity and Compound Properties of Piperidine-Based SARS-CoV-2 PLpro InhibitorsDale J Calleja, Nathan Kuchel, Bernadine G C Lu, et al.
Life Science Alliance|July 9, 2020
USP30 sets a trigger threshold for PINK1-PARKIN amplification of mitochondrial ubiquitylationEmma V Rusilowicz-Jones, Jane Jardine, Andreas Kallinos, et al.
Elife|October 12, 2021
USP28 deletion and small-molecule inhibition destabilizes c-MYC and elicits regression of squamous cell lung carcinomaE Josue Ruiz, Adan Pinto-Fernandez, Andrew P Turnbull, et al.
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