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Pharmacology & Therapeutics
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August 24, 2022
The next frontier in ADME science: Predicting transporter-based drug disposition, tissue concentrations and drug-drug interactions in humans
Flavia Storelli, Mengyue Yin, Aditya R Kumar, et al.
Molecular Pharmaceutics
|
February 25, 2016
Disruption of BSEP Function in HepaRG Cells Alters Bile Acid Disposition and Is a Susceptive Factor to Drug-Induced Cholestatic Injury
Xi Qiu, Yueping Zhang, Tongtong Liu, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
June 10, 2010
Novel metabolic bioactivation mechanism for a series of anti-inflammatory agents (2,5-diaminothiophene derivatives) mediated by cytochrome p450 enzymes
Yiding Hu, Shengtian Yang, F Barclay Shilliday, et al.
The AAPS Journal
|
March 12, 2026
Application of a Modified In Situ Perfusion Model to Quantify Intestinal Drug Excretion and Transporter-Mediated Interactions after Intravenous Administration
Rongjin Sun, Li Li, Lu Wang, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
February 9, 2013
Quantitative prediction of repaglinide-rifampicin complex drug interactions using dynamic and static mechanistic models: delineating differential CYP3A4 induction and OATP1B1 inhibition potential of rifampicin
Manthena V S Varma, Jian Lin, Yi-An Bi, et al.
European Journal of Medicinal Chemistry
|
July 31, 2012
Mechanistic insights from comparing intrinsic clearance values between human liver microsomes and hepatocytes to guide drug design
Li Di, Christopher Keefer, Dennis O Scott, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
January 10, 2019
A Comparison of Total and Plasma Membrane Abundance of Transporters in Suspended, Plated, Sandwich-Cultured Human Hepatocytes Versus Human Liver Tissue Using Quantitative Targeted Proteomics and Cell Surface Biotinylation
Vineet Kumar, Laurent Salphati, Cornelis E C A Hop, et al.
Acta Pharmaceutica Sinica. B
|
June 27, 2022
Recent advances in the translation of drug metabolism and pharmacokinetics science for drug discovery and development
Yurong Lai, Xiaoyan Chu, Li Di, et al.
Drug Metabolism and Pharmacokinetics
|
February 28, 2026
Applications of in vitro transporter assays for mechanistic characterization and prediction of clinical drug-drug interactions
Krisztina Herédi-Szabó, Sumito Ito, Xiaomin Liang, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
June 4, 2017
Comparative Evaluation of Plasma Bile Acids, Dehydroepiandrosterone Sulfate, Hexadecanedioate, and Tetradecanedioate with Coproporphyrins I and III as Markers of OATP Inhibition in Healthy Subjects
Hong Shen, Weiqi Chen, Dieter M Drexler, et al.
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of 14
Search research articles
Search
Showing results (91-100 of 136) with videos related to
Sort By:
Page
of 14
Pharmacology & Therapeutics
|
August 24, 2022
The next frontier in ADME science: Predicting transporter-based drug disposition, tissue concentrations and drug-drug interactions in humans
Flavia Storelli, Mengyue Yin, Aditya R Kumar, et al.
Molecular Pharmaceutics
|
February 25, 2016
Disruption of BSEP Function in HepaRG Cells Alters Bile Acid Disposition and Is a Susceptive Factor to Drug-Induced Cholestatic Injury
Xi Qiu, Yueping Zhang, Tongtong Liu, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
June 10, 2010
Novel metabolic bioactivation mechanism for a series of anti-inflammatory agents (2,5-diaminothiophene derivatives) mediated by cytochrome p450 enzymes
Yiding Hu, Shengtian Yang, F Barclay Shilliday, et al.
The AAPS Journal
|
March 12, 2026
Application of a Modified In Situ Perfusion Model to Quantify Intestinal Drug Excretion and Transporter-Mediated Interactions after Intravenous Administration
Rongjin Sun, Li Li, Lu Wang, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
February 9, 2013
Quantitative prediction of repaglinide-rifampicin complex drug interactions using dynamic and static mechanistic models: delineating differential CYP3A4 induction and OATP1B1 inhibition potential of rifampicin
Manthena V S Varma, Jian Lin, Yi-An Bi, et al.
European Journal of Medicinal Chemistry
|
July 31, 2012
Mechanistic insights from comparing intrinsic clearance values between human liver microsomes and hepatocytes to guide drug design
Li Di, Christopher Keefer, Dennis O Scott, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
January 10, 2019
A Comparison of Total and Plasma Membrane Abundance of Transporters in Suspended, Plated, Sandwich-Cultured Human Hepatocytes Versus Human Liver Tissue Using Quantitative Targeted Proteomics and Cell Surface Biotinylation
Vineet Kumar, Laurent Salphati, Cornelis E C A Hop, et al.
Acta Pharmaceutica Sinica. B
|
June 27, 2022
Recent advances in the translation of drug metabolism and pharmacokinetics science for drug discovery and development
Yurong Lai, Xiaoyan Chu, Li Di, et al.
Drug Metabolism and Pharmacokinetics
|
February 28, 2026
Applications of in vitro transporter assays for mechanistic characterization and prediction of clinical drug-drug interactions
Krisztina Herédi-Szabó, Sumito Ito, Xiaomin Liang, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
June 4, 2017
Comparative Evaluation of Plasma Bile Acids, Dehydroepiandrosterone Sulfate, Hexadecanedioate, and Tetradecanedioate with Coproporphyrins I and III as Markers of OATP Inhibition in Healthy Subjects
Hong Shen, Weiqi Chen, Dieter M Drexler, et al.
Page
of 14