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Bioorganic & Medicinal Chemistry Letters|October 24, 2002
Discovery of a potent and selective COX-2 inhibitor in the alkoxy lactone series with optimized metabolic profileYves Leblanc, Patrick Roy, Zhaoyin Wang, et al.Bioorganic & Medicinal Chemistry Letters|November 4, 2011
Nicotinic acids: liver-targeted SCD inhibitors with preclinical anti-diabetic efficacyDavid A Powell, W Cameron Black, Kelly Bleasby, et al.Bioorganic & Medicinal Chemistry Letters|August 2, 2016
Identification of potent, selective KDM5 inhibitorsVictor S Gehling, Steven F Bellon, Jean-Christophe Harmange, et al.Bioorganic & Medicinal Chemistry Letters|April 9, 2015
Development of methyl isoxazoleazepines as inhibitors of BETMichael C Hewitt, Yves Leblanc, Victor S Gehling, et al.ACS Medicinal Chemistry Letters|March 18, 2016
Discovery of Benzotriazolo[4,3-d][1,4]diazepines as Orally Active Inhibitors of BET BromodomainsAlexander M Taylor, Rishi G Vaswani, Victor S Gehling, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Discovery, Design, and Optimization of Isoxazole Azepine BET InhibitorsVictor S Gehling, Michael C Hewitt, Rishi G Vaswani, et al.Journal of Medicinal Chemistry|January 28, 2016
Identification of a Benzoisoxazoloazepine Inhibitor (CPI-0610) of the Bromodomain and Extra-Terminal (BET) Family as a Candidate for Human Clinical TrialsBrian K Albrecht, Victor S Gehling, Michael C Hewitt, et al.Journal of Medicinal Chemistry|August 5, 2022
GNE-064: A Potent, Selective, and Orally Bioavailable Chemical Probe for the Bromodomains of SMARCA2 and SMARCA4 and the Fifth Bromodomain of PBRM1Alexander M Taylor, Chris Bailey, Lisa D Belmont, et al.Bioorganic & Medicinal Chemistry Letters|November 26, 2010
Discovery of MK-7246, a selective CRTH2 antagonist for the treatment of respiratory diseasesMichel Gallant, Christian Beaulieu, Carl Berthelette, et al.ACS Medicinal Chemistry Letters|May 19, 2016
Fragment-Based Discovery of a Selective and Cell-Active Benzodiazepinone CBP/EP300 Bromodomain Inhibitor (CPI-637)Alexander M Taylor, Alexandre Côté, Michael C Hewitt, et al.Pageof 4