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Antimicrobial Agents and Chemotherapy|February 23, 2021
GS-9822, a preclinical LEDGIN candidate, displays a block-and-lock phenotype in cell cultureAnne Bruggemans, Gerlinde Vansant, Mini Balakrishnan, et al.European Journal of Medicinal Chemistry|February 5, 2008
The total synthesis of fukiic acid, an HIV-1 integrase inhibitorClémence Queffélec, Fabrice Bailly, Gladys Mbemba, et al.Human Gene Therapy|April 27, 2002
Characterization of lentiviral vector-mediated gene transfer in adult mouse brainVeerle Baekelandt, Anje Claeys, Kristel Eggermont, et al.Molecular Therapy : the Journal of the American Society of Gene Therapy|July 6, 2006
Noninvasive monitoring of long-term lentiviral vector-mediated gene expression in rodent brain with bioluminescence imagingChristophe M Deroose, Veerle Reumers, Rik Gijsbers, et al.Molecular Therapy. Nucleic Acids|March 7, 2013
Transient Expression of an LEDGF/p75 Chimera Retargets Lentivector Integration and Functionally Rescues in a Model for X-CGDSofie Vets, Jan De Rijck, Christian Brendel, et al.Journal of Medicinal Chemistry|March 21, 2008
Reaction of rosmarinic acid with nitrite ions in acidic conditions: discovery of nitro- and dinitrorosmarinic acids as new anti-HIV-1 agentsMélanie Dubois, Fabrice Bailly, Gladys Mbemba, et al.Human Gene Therapy|May 26, 2010
Rapid, simple, and versatile manufacturing of recombinant adeno-associated viral vectors at scaleMartin Lock, Mauricio Alvira, Luk H Vandenberghe, et al.Cancer Gene Therapy|April 2, 2021
LEDGF/p75-mediated chemoresistance of mixed-lineage leukemia involves cell survival pathways and super enhancer activatorsAlessandro Canella, Siska Van Belle, Tine Brouns, et al.Bioorganic & Medicinal Chemistry|August 30, 2013
Discovery of a novel 5-carbonyl-1H-imidazole-4-carboxamide class of inhibitors of the HIV-1 integrase-LEDGF/p75 interactionErik Serrao, Zhong-Liang Xu, Bikash Debnath, et al.Plos One|October 3, 2012
A symmetric region of the HIV-1 integrase dimerization interface is essential for viral replicationErik Serrao, Wannes Thys, Jonas Demeulemeester, et al.Pageof 27