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The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|October 30, 2021
Hyperexcitability and Pharmacological Responsiveness of Cortical Neurons Derived from Human iPSCs Carrying Epilepsy-Associated Sodium Channel Nav1.2-L1342P Genetic VariantZhefu Que, Maria I Olivero-Acosta, Jingliang Zhang, et al.
Molecular Psychiatry|March 19, 2024
Microglial over-pruning of synapses during development in autism-associated SCN2A-deficient mice and human cerebral organoidsJiaxiang Wu, Jingliang Zhang, Xiaoling Chen, et al.
Biorxiv : the Preprint Server for Biology|March 17, 2025
Restoration of excitation/inhibition balance enhances neuronal signal-to-noise ratio and rescues social deficits in autism-associated Scn2a-deficiencyJingliang Zhang, Muriel Eaton, Xiaoling Chen, et al.
Biorxiv : the Preprint Server for Biology|September 2, 2025
Epilepsy-Associated SCN2A-L1342P Mutation Drives Network Hyperexcitability and Widespread Transcriptomic Changes in Human Cortical OrganoidsMaria I Olivero-Acosta, Morgan Robinson, Zhefu Que, et al.
Biorxiv : the Preprint Server for Biology|June 12, 2025
Autism-associated SCN2A deficiency disrupts cortico-striatal circuitry in human brain assembloidsXiaoling Chen, Jingliang Zhang, Jiaxiang Wu, et al.
Epilepsia|July 30, 2026
Epilepsy-associated SCN2A-L1342P mutation drives network hyperexcitability and widespread transcriptomic changes in human cortical organoidsMaria I Olivero-Acosta, Morgan Robinson, Zhefu Que, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|November 18, 2024
Human iPSC-derived microglia sense and dampen hyperexcitability of cortical neurons carrying the epilepsy-associated SCN2A-L1342P mutationZhefu Que, Maria I Olivero-Acosta, Morgan Robinson, et al.
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