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The Journal of Clinical Investigation|July 7, 2026
ATR senses stiff extracellular matrix to promote epithelial-to-mesenchymal transition and immune suppressionXinyi Tu, Xiangyu Zeng, Yaoliang Sun, et al.Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy|April 18, 2024
Syk-dependent homologous recombination activation promotes cancer resistance to DNA targeted therapyQin Zhou, Xinyi Tu, Xiaonan Hou, et al.Nature Structural & Molecular Biology|January 8, 2026
Redox-driven ADAR1 activation promotes Okazaki fragment maturation and DNA replication integrityBin Chen, Guangchao Sun, Jake A Kloeber, et al.Molecular Cell|June 27, 2025
Isoform-specific function of NSD3 in DNA replication stress confers resistance to PARP inhibitors in prostate cancerShouhai Zhu, Huanyao Gao, Dan Jiang, et al.Nature Cancer|September 22, 2022
METTL16 antagonizes MRE11-mediated DNA end resection and confers synthetic lethality to PARP inhibition in pancreatic ductal adenocarcinomaXiangyu Zeng, Fei Zhao, Gaofeng Cui, et al.Signal Transduction and Targeted Therapy|May 10, 2023
A ribosomal gene panel predicting a novel synthetic lethality in non-BRCAness tumorsChao Zhang, Qiang Guo, Lifeng Chen, et al.Nature|December 13, 2019
A dominant autoinflammatory disease caused by non-cleavable variants of RIPK1Panfeng Tao, Jinqiao Sun, Zheming Wu, et al.Pageof 4