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Nucleic Acids Research|May 11, 2022
AGBE: a dual deaminase-mediated base editor by fusing CGBE with ABE for creating a saturated mutant population with multiple editing patternsYanhui Liang, Jingke Xie, Quanjun Zhang, et al.Genome Biology|January 17, 2023
Doxycycline-dependent Cas9-expressing pig resources for conditional in vivo gene nullification and activationQin Jin, Xiaoyi Liu, Zhenpeng Zhuang, et al.Cell|April 3, 2018
A Huntingtin Knockin Pig Model Recapitulates Features of Selective Neurodegeneration in Huntington's DiseaseSen Yan, Zhuchi Tu, Zhaoming Liu, et al.BMC Biology|September 24, 2020
ACBE, a new base editor for simultaneous C-to-T and A-to-G substitutions in mammalian systemsJingke Xie, Xingyun Huang, Xia Wang, et al.Stem Cell Reports|April 15, 2022
Generating functional cells through enhanced interspecies chimerism with human pluripotent stem cellsYanling Zhu, Zhishuai Zhang, Nana Fan, et al.Molecular Therapy : the Journal of the American Society of Gene Therapy|November 22, 2020
CRISPR/Cas9-Mediated Gene Correction in Newborn Rabbits with Hereditary Tyrosinemia Type INan Li, Shixue Gou, Jiaowei Wang, et al.Journal of Immunology (Baltimore, Md. : 1950)|September 22, 2020
Engineered Pigs Carrying a Gain-of-Function NLRP3 Homozygous Mutation Can Survive to Adulthood and Accurately Recapitulate Human Systemic Spontaneous Inflammatory ResponsesWenjing Li, Lei Shi, Zhenpeng Zhuang, et al.Nature Communications|June 30, 2019
Efficient base editing for multiple genes and loci in pigs using base editorsJingke Xie, Weikai Ge, Nan Li, et al.Communications Biology|November 3, 2022
Multiplexed base editing through Cas12a variant-mediated cytosine and adenine base editorsFangbing Chen, Meng Lian, Bingxiu Ma, et al.Cell Stem Cell|September 8, 2023
Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementationJiaowei Wang, Wenguang Xie, Nan Li, et al.Pageof 18