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Journal of Medicinal Chemistry
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August 12, 2025
Discovery of Tamsulosin Derivatives with Shifted Selectivity from the α<sub>1</sub>-Adrenergic Receptor to ANO1 as Potent Antiosteoporotic Agents
Chaoquan Tian, Weijia Sun, Tao Yu, et al.
Journal of Medicinal Chemistry
|
May 29, 2024
Discovery of Novel Non-Nucleoside Inhibitors Interacting with Dizinc Ions of CD73
Cunjian Shi, Longfeng Chang, Jie Wang, et al.
Journal of Medicinal Chemistry
|
January 30, 2019
Discovery of a Natural-Product-Derived Preclinical Candidate for Once-Weekly Treatment of Type 2 Diabetes
Shiliang Li, Chun Qin, Shichao Cui, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
December 31, 2024
Tamsulosin ameliorates bone loss by inhibiting the release of Cl<sup>-</sup> through wedging into an allosteric site of TMEM16A
Shiliang Li, Weijia Sun, Shuang Li, et al.
Innovation (Cambridge (Mass.))
|
July 9, 2026
Design and development of novel EGFR inhibitors spanning all subgroups of EGFR mutations in non-small cell lung cancer
Caolin Wang, Yiting Cen, Manzhan Zhang, et al.
European Journal of Medicinal Chemistry
|
September 15, 2024
Design, synthesis, and biological evaluation of diphenyl ether substituted quinazolin-4-amine derivatives as potent EGFR<sup>L858R/T790M/C797S</sup> inhibitors
Dou Dou, Xingsen Zhang, Jie Wang, et al.
Circulation
|
June 16, 2025
Inactivation of RhoA for Hypertension Treatment Through the TRPV4-RhoA-RhoGDI1 Axis
Jiawen Wang, Zhen Yuan, Na Yu, et al.
Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
|
April 26, 2025
Dual-Locking the SARS-CoV-2 Spike Trimer: An Amphipathic Molecular "Bolt" Stabilizes Conserved Druggable Interfaces for Coronavirus Inhibition
Shiliang Li, Fang Ye, Yucheng Zheng, et al.
Journal of Medicinal Chemistry
|
July 12, 2016
Discovery and Rational Design of Natural-Product-Derived 2-Phenyl-3,4-dihydro-2H-benzo[f]chromen-3-amine Analogs as Novel and Potent Dipeptidyl Peptidase 4 (DPP-4) Inhibitors for the Treatment of Type 2 Diabetes
Shiliang Li, Hongling Xu, Shichao Cui, et al.
Protein & Cell
|
August 6, 2020
Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2
Rui Xiong, Leike Zhang, Shiliang Li, et al.
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Search research articles
Search
Showing results (81-90 of 93) with videos related to
Sort By:
Page
of 10
Journal of Medicinal Chemistry
|
August 12, 2025
Discovery of Tamsulosin Derivatives with Shifted Selectivity from the α<sub>1</sub>-Adrenergic Receptor to ANO1 as Potent Antiosteoporotic Agents
Chaoquan Tian, Weijia Sun, Tao Yu, et al.
Journal of Medicinal Chemistry
|
May 29, 2024
Discovery of Novel Non-Nucleoside Inhibitors Interacting with Dizinc Ions of CD73
Cunjian Shi, Longfeng Chang, Jie Wang, et al.
Journal of Medicinal Chemistry
|
January 30, 2019
Discovery of a Natural-Product-Derived Preclinical Candidate for Once-Weekly Treatment of Type 2 Diabetes
Shiliang Li, Chun Qin, Shichao Cui, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
December 31, 2024
Tamsulosin ameliorates bone loss by inhibiting the release of Cl<sup>-</sup> through wedging into an allosteric site of TMEM16A
Shiliang Li, Weijia Sun, Shuang Li, et al.
Innovation (Cambridge (Mass.))
|
July 9, 2026
Design and development of novel EGFR inhibitors spanning all subgroups of EGFR mutations in non-small cell lung cancer
Caolin Wang, Yiting Cen, Manzhan Zhang, et al.
European Journal of Medicinal Chemistry
|
September 15, 2024
Design, synthesis, and biological evaluation of diphenyl ether substituted quinazolin-4-amine derivatives as potent EGFR<sup>L858R/T790M/C797S</sup> inhibitors
Dou Dou, Xingsen Zhang, Jie Wang, et al.
Circulation
|
June 16, 2025
Inactivation of RhoA for Hypertension Treatment Through the TRPV4-RhoA-RhoGDI1 Axis
Jiawen Wang, Zhen Yuan, Na Yu, et al.
Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
|
April 26, 2025
Dual-Locking the SARS-CoV-2 Spike Trimer: An Amphipathic Molecular "Bolt" Stabilizes Conserved Druggable Interfaces for Coronavirus Inhibition
Shiliang Li, Fang Ye, Yucheng Zheng, et al.
Journal of Medicinal Chemistry
|
July 12, 2016
Discovery and Rational Design of Natural-Product-Derived 2-Phenyl-3,4-dihydro-2H-benzo[f]chromen-3-amine Analogs as Novel and Potent Dipeptidyl Peptidase 4 (DPP-4) Inhibitors for the Treatment of Type 2 Diabetes
Shiliang Li, Hongling Xu, Shichao Cui, et al.
Protein & Cell
|
August 6, 2020
Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2
Rui Xiong, Leike Zhang, Shiliang Li, et al.
Page
of 10