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JCI Insight|November 5, 2024
All-in-one AAV-mediated Nrl gene inactivation rescues retinal degeneration in Pde6a miceZhiquan Liu, Siyu Chen, Chien-Hui Lo, et al.
Human Molecular Genetics|April 1, 2024
Base editing correction of OCRL in Lowe syndrome: ABE-mediated functional rescue in patient-derived fibroblastsSiyu Chen, Chien-Hui Lo, Zhiquan Liu, et al.
Nature Communications|February 2, 2022
Inhibition of base editors with anti-deaminases derived from virusesZhiquan Liu, Siyu Chen, Liangxue Lai, et al.
The CRISPR Journal|March 3, 2022
Efficient C-to-G Base Editing with Improved Target Compatibility Using Engineered Deaminase-nCas9 FusionsSiyu Chen, Zhiquan Liu, Liangxue Lai, et al.
Biorxiv : the Preprint Server for Biology|November 18, 2024
Defective Neurogenesis in Lowe Syndrome is Caused by Mitochondria Loss and Cilia-related Sonic Hedgehog DefectsChien-Hui Lo, Siyu Chen, Jingyu Zhao, et al.
Journal of Genetics and Genomics = Yi Chuan Xue Bao|April 14, 2022
Efficient multinucleotide deletions using deaminase-Cas9 fusions in human cellsSiyu Chen, Zhiquan Liu, Hao Yu, et al.
PNAS Nexus|June 27, 2025
Gene therapy for ocular hypertension using hfCas13d-mediated mRNA targetingSiyu Chen, Zhiquan Liu, Chien-Hui Lo, et al.
Survey of Ophthalmology|June 5, 2025
Pathophysiology of intraoperative floppy iris syndrome: An unsettled debateYingchun Shen, Rachel Frauches, Jingyu Zhao, et al.
The CRISPR Journal|June 10, 2022
Compact Cje3Cas9 for Efficient In Vivo Genome Editing and Adenine Base EditingSiyu Chen, Zhiquan Liu, Wanhua Xie, et al.
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