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Journal of Medicinal Chemistry
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May 14, 2026
Dual Allosteric Targeting of SHP2: Development of Bivalent Inhibitors with Enhanced Potency for Cancer Treatment
Chengchun Zhu, Yang Zhang, Yaran Jin, et al.
EMBO Molecular Medicine
|
July 30, 2016
A new hERG allosteric modulator rescues genetic and drug-induced long-QT syndrome phenotypes in cardiomyocytes from isogenic pairs of patient induced pluripotent stem cells
Luca Sala, Zhiyi Yu, Dorien Ward-van Oostwaard, et al.
Circulation. Arrhythmia and Electrophysiology
|
April 14, 2016
Allosteric Modulation of Kv11.1 (hERG) Channels Protects Against Drug-Induced Ventricular Arrhythmias
Zhiyi Yu, Jia Liu, Jacobus P D van Veldhoven, et al.
Pharmacology Research & Perspectives
|
January 19, 2017
Application of a systems pharmacology model for translational prediction of hERG-mediated QTc prolongation
Verena Gotta, Zhiyi Yu, Frank Cools, et al.
Neurochemical Research
|
January 4, 2021
Properties of Calmodulin Binding to Na<sub>V</sub>1.2 IQ Motif and Its Autism-Associated Mutation R1902C
Wanying Jia, Junyan Liu, Zhiyi Yu, et al.
Biochemical Pharmacology
|
March 26, 2019
Long residence time adenosine A<sub>1</sub> receptor agonists produce sustained wash-resistant antilipolytic effect in rat adipocytes
Yi Yun, Jianmin Chen, Rongfang Liu, et al.
Nature Communications
|
March 14, 2026
A guard cell carbonic anhydrase binds and regulates SLAC1 separate from its catalytic activity
Lingfeng Xia, Jonas Chaves Alvim, Thanh-Hao Nguyen, et al.
Journal of Medicinal Chemistry
|
June 9, 2026
SHP2 Inhibition Reveals Compensatory PI3K-AKT Activation in KRAS-Driven Pancreatic Cancer: Discovery of <b>SDUY104</b> and Rational Approaches for Combination Therapy
Chengchun Zhu, Chen Wang, Yijie Zhu, et al.
Journal of Medicinal Chemistry
|
July 1, 2015
Structure-Affinity Relationships (SARs) and Structure-Kinetics Relationships (SKRs) of Kv11.1 Blockers
Zhiyi Yu, Jacobus P D van Veldhoven, Julien Louvel, et al.
European Journal of Medicinal Chemistry
|
April 5, 2020
A potent photoreactive general anesthetic with novel binding site selectivity for GABA<sub>A</sub> receptors
Abdelrahman R Shalabi, Zhiyi Yu, Xiaojuan Zhou, et al.
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Search research articles
Search
Showing results (41-50 of 56) with videos related to
Sort By:
Page
of 6
Journal of Medicinal Chemistry
|
May 14, 2026
Dual Allosteric Targeting of SHP2: Development of Bivalent Inhibitors with Enhanced Potency for Cancer Treatment
Chengchun Zhu, Yang Zhang, Yaran Jin, et al.
EMBO Molecular Medicine
|
July 30, 2016
A new hERG allosteric modulator rescues genetic and drug-induced long-QT syndrome phenotypes in cardiomyocytes from isogenic pairs of patient induced pluripotent stem cells
Luca Sala, Zhiyi Yu, Dorien Ward-van Oostwaard, et al.
Circulation. Arrhythmia and Electrophysiology
|
April 14, 2016
Allosteric Modulation of Kv11.1 (hERG) Channels Protects Against Drug-Induced Ventricular Arrhythmias
Zhiyi Yu, Jia Liu, Jacobus P D van Veldhoven, et al.
Pharmacology Research & Perspectives
|
January 19, 2017
Application of a systems pharmacology model for translational prediction of hERG-mediated QTc prolongation
Verena Gotta, Zhiyi Yu, Frank Cools, et al.
Neurochemical Research
|
January 4, 2021
Properties of Calmodulin Binding to Na<sub>V</sub>1.2 IQ Motif and Its Autism-Associated Mutation R1902C
Wanying Jia, Junyan Liu, Zhiyi Yu, et al.
Biochemical Pharmacology
|
March 26, 2019
Long residence time adenosine A<sub>1</sub> receptor agonists produce sustained wash-resistant antilipolytic effect in rat adipocytes
Yi Yun, Jianmin Chen, Rongfang Liu, et al.
Nature Communications
|
March 14, 2026
A guard cell carbonic anhydrase binds and regulates SLAC1 separate from its catalytic activity
Lingfeng Xia, Jonas Chaves Alvim, Thanh-Hao Nguyen, et al.
Journal of Medicinal Chemistry
|
June 9, 2026
SHP2 Inhibition Reveals Compensatory PI3K-AKT Activation in KRAS-Driven Pancreatic Cancer: Discovery of <b>SDUY104</b> and Rational Approaches for Combination Therapy
Chengchun Zhu, Chen Wang, Yijie Zhu, et al.
Journal of Medicinal Chemistry
|
July 1, 2015
Structure-Affinity Relationships (SARs) and Structure-Kinetics Relationships (SKRs) of Kv11.1 Blockers
Zhiyi Yu, Jacobus P D van Veldhoven, Julien Louvel, et al.
European Journal of Medicinal Chemistry
|
April 5, 2020
A potent photoreactive general anesthetic with novel binding site selectivity for GABA<sub>A</sub> receptors
Abdelrahman R Shalabi, Zhiyi Yu, Xiaojuan Zhou, et al.
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of 6