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Antimicrobial Agents and Chemotherapy|February 26, 2004
Interactions between penicillin-binding proteins (PBPs) and two novel classes of PBP inhibitors, arylalkylidene rhodanines and arylalkylidene iminothiazolidin-4-onesAstrid Zervosen, Wei-Ping Lu, Zhouliang Chen, et al.Journal of Medicinal Chemistry|January 29, 2019
Optimization of Fused Bicyclic Allosteric SHP2 InhibitorsJeffrey T Bagdanoff, Zhouliang Chen, Michael Acker, et al.ACS Chemical Biology|January 6, 2018
Dual Allosteric Inhibition of SHP2 PhosphataseMichelle Fodor, Edmund Price, Ping Wang, et al.Journal of Medicinal Chemistry|January 29, 2019
6-Amino-3-methylpyrimidinones as Potent, Selective, and Orally Efficacious SHP2 InhibitorsPatrick Sarver, Michael Acker, Jeffrey T Bagdanoff, et al.Journal of Medicinal Chemistry|July 13, 2013
Identification of NVP-TNKS656: the use of structure-efficiency relationships to generate a highly potent, selective, and orally active tankyrase inhibitorMichael D Shultz, Atwood K Cheung, Christina A Kirby, et al.Journal of Medicinal Chemistry|June 28, 2016
Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase InhibitorJorge Garcia Fortanet, Christine Hiu-Tung Chen, Ying-Nan P Chen, et al.Nature|July 1, 2016
Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinasesYing-Nan P Chen, Matthew J LaMarche, Ho Man Chan, et al.Journal of Medicinal Chemistry|September 10, 2020
Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of CancerMatthew J LaMarche, Michael Acker, Andreea Argintaru, et al.Pageof 1