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Journal of Immunology (Baltimore, Md. : 1950)|August 5, 2020
Middle East Respiratory Syndrome Coronavirus ORF8b Accessory Protein Suppresses Type I IFN Expression by Impeding HSP70-Dependent Activation of IRF3 Kinase IKKεLok-Yin Roy Wong, Zi-Wei Ye, Pak-Yin Lui, et al.
Pharmacological Research|May 31, 2020
Discovery of the FDA-approved drugs bexarotene, cetilistat, diiodohydroxyquinoline, and abiraterone as potential COVID-19 treatments with a robust two-tier screening systemShuofeng Yuan, Jasper F W Chan, Kenn K H Chik, et al.
Computational and Structural Biotechnology Journal|October 29, 2021
Severe fever with thrombocytopenia syndrome virus (SFTSV)-host interactome screen identifies viral nucleoprotein-associated host factors as potential antiviral targetsJianli Cao, Gang Lu, Lei Wen, et al.
EMBO Reports|August 15, 2018
Inhibition of AIM2 inflammasome activation by a novel transcript isoform of IFI16Pei-Hui Wang, Zi-Wei Ye, Jian-Jun Deng, et al.
Viruses|April 28, 2019
Screening of an FDA-Approved Drug Library with a Two-Tier System Identifies an Entry Inhibitor of Severe Fever with Thrombocytopenia Syndrome VirusShuofeng Yuan, Jasper Fuk-Woo Chan, Zi-Wei Ye, et al.
Emerging Microbes & Infections|February 4, 2021
Beneficial effect of combinational methylprednisolone and remdesivir in hamster model of SARS-CoV-2 infectionZi-Wei Ye, Shuofeng Yuan, Jasper Fuk-Woo Chan, et al.
International Journal of Biological Sciences|April 28, 2021
In silico structure-based discovery of a SARS-CoV-2 main protease inhibitorLei Wen, Kaiming Tang, Kenn Ka-Heng Chik, et al.
Cellular & Molecular Immunology|March 30, 2022
Intranasal administration of a single dose of a candidate live attenuated vaccine derived from an NSP16-deficient SARS-CoV-2 strain confers sterilizing immunity in animalsZi-Wei Ye, Chon Phin Ong, Kaiming Tang, et al.
Viruses|October 26, 2021
In Silico Structure-Based Design of Antiviral Peptides Targeting the Severe Fever with Thrombocytopenia Syndrome Virus Glycoprotein GnShuo-Feng Yuan, Lei Wen, Kenn Ka-Heng Chik, et al.
Viruses|June 14, 2020
Broad-Spectrum Host-Based Antivirals Targeting the Interferon and Lipogenesis Pathways as Potential Treatment Options for the Pandemic Coronavirus Disease 2019 (COVID-19)Shuofeng Yuan, Chris Chun-Yiu Chan, Kenn Ka-Heng Chik, et al.
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