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Science (New York, N.Y.)|March 28, 2024
Pyrimidines maintain mitochondrial pyruvate oxidation to support de novo lipogenesisUmakant Sahu, Elodie Villa, Colleen R Reczek, et al.Genes & Development|December 22, 2018
Regulation of MLL/COMPASS stability through its proteolytic cleavage by taspase1 as a possible approach for clinical therapy of leukemiaZibo Zhao, Lu Wang, Andrew G Volk, et al.Science Advances|November 13, 2018
TET2 coactivates gene expression through demethylation of enhancersLu Wang, Patrick A Ozark, Edwin R Smith, et al.The Journal of Clinical Investigation|May 30, 2023
Therapeutic targeting of metabolic vulnerabilities in cancers with MLL3/4-COMPASS epigenetic regulator mutationsZibo Zhao, Kaixiang Cao, Jun Watanabe, et al.Nature Communications|February 17, 2026
Recruitment of BRD4 to the ASXL1 genomic targets depends on the extra-terminal domain of BRD4Karthik Selvam, Shuang Lu, Clémence Messmer, et al.Nature Genetics|May 13, 2020
Uncoupling histone H3K4 trimethylation from developmental gene expression via an equilibrium of COMPASS, Polycomb and DNA methylationDelphine Douillet, Christie C Sze, Caila Ryan, et al.Nature Medicine|May 23, 2018
Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapyLu Wang, Zibo Zhao, Patrick A Ozark, et al.Oncogene|January 26, 2018
A Carcinogen-induced mouse model recapitulates the molecular alterations of human muscle invasive bladder cancerDamiano Fantini, Alexander P Glaser, Kalen J Rimar, et al.Genome Research|August 24, 2021
A ChIP-exo screen of 887 Protein Capture Reagents Program transcription factor antibodies in human cellsWilliam K M Lai, Luca Mariani, Gerson Rothschild, et al.Nature Cell Biology|September 25, 2023
Iron drives anabolic metabolism through active histone demethylation and mTORC1Jason S Shapiro, Hsiang-Chun Chang, Yuki Tatekoshi, et al.Pageof 6