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Advanced Materials (Deerfield Beach, Fla.)|October 3, 2018
Nanoparticle-Conjugate TLR7/8 Agonist Localized Immunotherapy Provokes Safe Antitumoral ResponsesLutz Nuhn, Stefaan De Koker, Sandra Van Lint, et al.
Biomaterials|July 12, 2024
CO-DELIVERY of glutamic acid-extended peptide antigen and imidazoquinoline TLR7/8 agonist via ionizable lipid nanoparticles induces protective anti-tumor immunityTingting Ye, Zifu Zhong, Federica Cappellesso, et al.
Journal of the American Chemical Society|June 12, 2020
Potent and Prolonged Innate Immune Activation by Enzyme-Responsive Imidazoquinoline TLR7/8 Agonist Prodrug VesiclesBi Wang, Simon Van Herck, Yong Chen, et al.
Angewandte Chemie (International Ed. in English)|May 1, 2025
Thioamides Adjacent to the Ionizable Amine Headgroup in Ionizable Lipids Reduce the pK<sub>a</sub> of Lipid Nanoparticles and Enhance mRNA Transfection Efficiency in Vitro and in VivoYong Chen, Emily De Lombaerde, Aimée Bugler-Lamb, et al.
Angewandte Chemie (International Ed. in English)|August 10, 2019
Potent Lymphatic Translocation and Spatial Control Over Innate Immune Activation by Polymer-Lipid Amphiphile Conjugates of Small-Molecule TLR7/8 AgonistsJana De Vrieze, Benoit Louage, Kim Deswarte, et al.
ACS Applied Materials & Interfaces|January 28, 2021
Lipid-Polyglutamate Nanoparticle Vaccine PlatformDorien Van Lysebetten, Alessio Malfanti, Kim Deswarte, et al.
Angewandte Chemie (International Ed. in English)|October 23, 2024
A Fentanyl Hapten-Displaying Lipid Nanoparticle Vaccine that Non-Covalently Encapsulates a TLR7/8 Agonist and T-Helper Epitope Induces Protective Anti-Fentanyl ImmunityZifu Zhong, Marie H Deventer, Yong Chen, et al.
Biorxiv : the Preprint Server for Biology|October 27, 2020
Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Modified Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein VaccineSonia Jangra, Jana De Vrieze, Angela Choi, et al.
Angewandte Chemie (International Ed. in English)|January 19, 2021
Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Lipid Amphiphile Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine*Sonia Jangra, Jana De Vrieze, Angela Choi, et al.
Small (Weinheim an Der Bergstrasse, Germany)|October 23, 2023
Lipid Nanoparticle Encapsulation Empowers Poly(I:C) to Activate Cytoplasmic RLRs and Thereby Increases Its AdjuvanticityAlexander Lamoot, Sonia Jangra, Gabriel Laghlali, et al.
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