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Frontiers in Oncology|December 16, 2020
PROTAC Bromodomain Inhibitor ARV-825 Displays Anti-Tumor Activity in Neuroblastoma by Repressing Expression of MYCN or c-MycZhiheng Li, Su Lin Lim, Yanfang Tao, et al.Hematology (Amsterdam, Netherlands)|August 18, 2023
BRD4 PROTAC degrader MZ1 exhibits anti-B-cell acute lymphoblastic leukemia effects via targeting CCND3Li Ma, Jianwei Wang, Yang Yang, et al.Cell & Bioscience|September 16, 2022
Super-enhancer-associated INSM2 regulates lipid metabolism by modulating mTOR signaling pathway in neuroblastomaHaibo Cao, Ran Zhuo, Zimu Zhang, et al.Journal of Translational Medicine|February 11, 2026
NeuroD1-USP1-MYCN axis drives tumor progression in neuroblastomaGen Li, Yanling Chen, Ran Zhuo, et al.Cellular Signalling|April 15, 2025
The super-enhancer regulatory gene SH2D1A promotes the progression of T cell acute lymphoblastic leukemia by activating CHI3L2Wanyan Jiao, Juanjuan Yu, Zimu Zhang, et al.Cell Death & Disease|August 12, 2023
LMO2 promotes the development of AML through interaction with transcription co-regulator LDB1Lihui Lu, Jianwei Wang, Fang Fang, et al.Journal of Experimental & Clinical Cancer Research : CR|October 10, 2024
Enhancer looping protein LDB1 modulates MYB expression in T-ALL cell lines in vitro by cooperating with master transcription factorsYan Li, Zimu Zhang, Juanjuan Yu, et al.International Journal of Biological Sciences|March 9, 2026
USP20, a Super-enhancer Regulated Gene, Promotes Acute Myeloid Leukemia Progression through CTNNB1 DeubiquitinationJia Cheng, Fang Fang, Zhiheng Li, et al.Advanced Science (Weinheim, Baden-Wurttemberg, Germany)|October 25, 2024
Super-Enhancer-Driven IRF2BP2 is Activated by Master Transcription Factors and Sustains T-ALL Cell Growth and SurvivalJuanjuan Yu, Zimu Zhang, Yanling Chen, et al.Journal of Experimental & Clinical Cancer Research : CR|July 23, 2024
Targeting RBM39 through indisulam induced mis-splicing of mRNA to exert anti-cancer effects in T-cell acute lymphoblastic leukemiaTongting Ji, Yang Yang, Juanjuan Yu, et al.Pageof 10