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Future Medicinal Chemistry|March 11, 2025
Recent advances in targeted degradation in the RAS pathwayZhiming Ge, Zisheng Fan, Wei He, et al.ACS Medicinal Chemistry Letters|February 14, 2024
Synthesis and Biological Evaluation of β-Lactam Derivatives Targeting Speckle-Type POZ Protein (SPOP)Chenmao Zhou, Xinyue Hao, Zhengyang Chen, et al.Journal of Medicinal Chemistry|March 1, 2022
Discovery of the First-in-Class Agonist-Based SOS1 PROTACs Effective in Human Cancer Cells Harboring Various KRAS MutationsChuan Zhou, Zisheng Fan, Zehui Zhou, et al.Acta Pharmaceutica Sinica. B|June 1, 2022
Discovery of ARF1-targeting inhibitor demethylzeylasteral as a potential agent against breast cancerJie Chang, Ruirui Yang, Lifan Chen, et al.Journal of Medicinal Chemistry|November 15, 2021
Active Learning for Drug Design: A Case Study on the Plasma Exposure of Orally Administered DrugsXiaoyu Ding, Rongrong Cui, Jie Yu, et al.Journal of Medicinal Chemistry|January 10, 2024
Design, Synthesis, and Biological Evaluation of Potent and Selective PROTAC Degraders of Oncogenic KRASG12DChuan Zhou, Zisheng Fan, Yuejiao Gu, et al.Science China. Life Sciences|August 27, 2024
Targeting STING oligomerization with licochalcone D ameliorates STING-driven inflammatory diseasesYinghui Zhang, Yadan Liu, Bing Jiang, et al.Protein & Cell|October 22, 2021
Drug target inference by mining transcriptional data using a novel graph convolutional network frameworkFeisheng Zhong, Xiaolong Wu, Ruirui Yang, et al.Journal of Medicinal Chemistry|March 10, 2023
Discovery of a Potent, Cooperative, and Selective SOS1 PROTAC ZZ151 with In Vivo Antitumor Efficacy in KRAS-Mutant CancersZehui Zhou, Guizhen Zhou, Chuan Zhou, et al.Advanced Science (Weinheim, Baden-Wurttemberg, Germany)|November 19, 2024
Ginkgetin Alleviates Inflammation and Senescence by Targeting STINGYadan Liu, Jialin Ye, Zisheng Fan, et al.Pageof 2