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Molecular Pharmacology
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October 25, 2011
Functional impact of allosteric agonist activity of selective positive allosteric modulators of metabotropic glutamate receptor subtype 5 in regulating central nervous system function
Meredith J Noetzel, Jerri M Rook, Paige N Vinson, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
October 29, 2015
Allosteric activation of M4 muscarinic receptors improve behavioral and physiological alterations in early symptomatic YAC128 mice
Tristano Pancani, Daniel J Foster, Mark S Moehle, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
October 28, 2015
VU0477573: Partial Negative Allosteric Modulator of the Subtype 5 Metabotropic Glutamate Receptor with In Vivo Efficacy
Hilary Highfield Nickols, Joannes P Yuh, Karen J Gregory, et al.
Journal of Medicinal Chemistry
|
September 21, 2013
Exploration of allosteric agonism structure-activity relationships within an acetylene series of metabotropic glutamate receptor 5 (mGlu5) positive allosteric modulators (PAMs): discovery of 5-((3-fluorophenyl)ethynyl)-N-(3-methyloxetan-3-yl)picolinamide (ML254)
Mark Turlington, Meredith J Noetzel, Aspen Chun, et al.
Molecular Pharmacology
|
July 31, 2008
Discovery, characterization, and antiparkinsonian effect of novel positive allosteric modulators of metabotropic glutamate receptor 4
Colleen M Niswender, Kari A Johnson, C David Weaver, et al.
Biological Psychiatry
|
November 13, 2012
Unique signaling profiles of positive allosteric modulators of metabotropic glutamate receptor subtype 5 determine differences in in vivo activity
Jerri M Rook, Meredith J Noetzel, Wendy A Pouliot, et al.
ACS Chemical Neuroscience
|
March 25, 2025
Application of Deuterium in an M<sub>1</sub> Positive Allosteric Modulator Back-Up Program: The Discovery of VU6045422
Julie L Engers, Jinming Li, Changho Han, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
|
October 10, 2008
Novel selective allosteric activator of the M1 muscarinic acetylcholine receptor regulates amyloid processing and produces antipsychotic-like activity in rats
Carrie K Jones, Ashley E Brady, Albert A Davis, et al.
ACS Chemical Neuroscience
|
August 28, 2024
Discovery of VU6007496: Challenges in the Development of an M<sub>1</sub> Positive Allosteric Modulator Backup Candidate
Julie L Engers, Katrina A Bollinger, Rory A Capstick, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
|
November 13, 2009
A selective allosteric potentiator of the M1 muscarinic acetylcholine receptor increases activity of medial prefrontal cortical neurons and restores impairments in reversal learning
Jana K Shirey, Ashley E Brady, Paulianda J Jones, et al.
Page
of 6
Search research articles
Search
Showing results (41-50 of 56) with videos related to
Sort By:
Page
of 6
Molecular Pharmacology
|
October 25, 2011
Functional impact of allosteric agonist activity of selective positive allosteric modulators of metabotropic glutamate receptor subtype 5 in regulating central nervous system function
Meredith J Noetzel, Jerri M Rook, Paige N Vinson, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
October 29, 2015
Allosteric activation of M4 muscarinic receptors improve behavioral and physiological alterations in early symptomatic YAC128 mice
Tristano Pancani, Daniel J Foster, Mark S Moehle, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
October 28, 2015
VU0477573: Partial Negative Allosteric Modulator of the Subtype 5 Metabotropic Glutamate Receptor with In Vivo Efficacy
Hilary Highfield Nickols, Joannes P Yuh, Karen J Gregory, et al.
Journal of Medicinal Chemistry
|
September 21, 2013
Exploration of allosteric agonism structure-activity relationships within an acetylene series of metabotropic glutamate receptor 5 (mGlu5) positive allosteric modulators (PAMs): discovery of 5-((3-fluorophenyl)ethynyl)-N-(3-methyloxetan-3-yl)picolinamide (ML254)
Mark Turlington, Meredith J Noetzel, Aspen Chun, et al.
Molecular Pharmacology
|
July 31, 2008
Discovery, characterization, and antiparkinsonian effect of novel positive allosteric modulators of metabotropic glutamate receptor 4
Colleen M Niswender, Kari A Johnson, C David Weaver, et al.
Biological Psychiatry
|
November 13, 2012
Unique signaling profiles of positive allosteric modulators of metabotropic glutamate receptor subtype 5 determine differences in in vivo activity
Jerri M Rook, Meredith J Noetzel, Wendy A Pouliot, et al.
ACS Chemical Neuroscience
|
March 25, 2025
Application of Deuterium in an M<sub>1</sub> Positive Allosteric Modulator Back-Up Program: The Discovery of VU6045422
Julie L Engers, Jinming Li, Changho Han, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
|
October 10, 2008
Novel selective allosteric activator of the M1 muscarinic acetylcholine receptor regulates amyloid processing and produces antipsychotic-like activity in rats
Carrie K Jones, Ashley E Brady, Albert A Davis, et al.
ACS Chemical Neuroscience
|
August 28, 2024
Discovery of VU6007496: Challenges in the Development of an M<sub>1</sub> Positive Allosteric Modulator Backup Candidate
Julie L Engers, Katrina A Bollinger, Rory A Capstick, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
|
November 13, 2009
A selective allosteric potentiator of the M1 muscarinic acetylcholine receptor increases activity of medial prefrontal cortical neurons and restores impairments in reversal learning
Jana K Shirey, Ashley E Brady, Paulianda J Jones, et al.
Page
of 6