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Methods in Molecular Biology (Clifton, N.J.)|May 20, 2011
Repair of CFTR folding defects with correctors that function as pharmacological chaperonesTip W Loo, David M ClarkeThe Journal of Biological Chemistry|October 29, 2015
Mapping the Binding Site of the Inhibitor Tariquidar That Stabilizes the First Transmembrane Domain of P-glycoproteinTip W Loo, David M ClarkeBiochemical Pharmacology|December 3, 2014
Tariquidar inhibits P-glycoprotein drug efflux but activates ATPase activity by blocking transition to an open conformationTip W Loo, David M ClarkeBiochemical Pharmacology|January 14, 2014
The cystic fibrosis V232D mutation inhibits CFTR maturation by disrupting a hydrophobic pocket rather than formation of aberrant interhelical hydrogen bondsTip W Loo, David M ClarkeInternational Journal of Health Policy and Management|August 6, 2025
Barriers and Enablers of Value-Based Procurement in Dutch Healthcare ProvidersBarbara Tip, Niels Uenk, Fredo SchotanusThe Journal of Biological Chemistry|February 14, 2014
Identification of the distance between the homologous halves of P-glycoprotein that triggers the high/low ATPase activity switchTip W Loo, David M ClarkeBiochemical and Biophysical Research Communications|December 28, 2016
Attachment of a 'molecular spring' restores drug-stimulated ATPase activity to P-glycoprotein lacking both Q loop glutaminesTip W Loo, David M ClarkeArchives of Biochemistry and Biophysics|March 11, 2008
Mutational analysis of ABC proteinsTip W Loo, David M ClarkeBiochemistry|May 3, 2013
A salt bridge in intracellular loop 2 is essential for folding of human p-glycoproteinTip W Loo, David M ClarkeThe Journal of Biological Chemistry|November 27, 2013
Locking intracellular helices 2 and 3 together inactivates human P-glycoproteinTip W Loo, David M ClarkePageof 70