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ACS Medicinal Chemistry Letters|July 16, 2025
Novel 5‑[2,7-Diazaspiro[3.5]nonan-7-yl]-5-[4-phenoxyphenyl]hexahydropyrimidine-2,4,6-trione Derivatives as MMP9 Inhibitors for Treating Ocular Surface Diseases, in Particular Dry Eye DiseaseRam W SabnisACS Medicinal Chemistry Letters|July 16, 2025
Design, Synthesis, and Protective Effect Evaluation on Myocardial Ischemia of New Triazole Aldehyde Dehydrogenase 2 ActivatorsFengping Zhao, Xin Pan, Xi Chen, et al.ACS Medicinal Chemistry Letters|December 17, 2025
Discovery of a Potent c‑MET Inhibitor for Non-Small Cell Lung Cancer Treatment by AI-Based and Docking-Based Virtual ScreeningQi Shen, He Li, Minyu Cheng, et al.ACS Medicinal Chemistry Letters|December 17, 2025
Novel Thio-Substituted 1,3,5-Triazine Compounds as CX3CR1 Modulators for Treating Cardiovascular DiseasesRam W SabnisACS Medicinal Chemistry Letters|December 17, 2025
Novel Compounds as ACC Inhibitors for Treating AcneRam W SabnisACS Medicinal Chemistry Letters|December 17, 2025
Synthesis and Evaluation of Novel Aza-Aromatics as Dual 5‑HT2A and 5‑HT2C Receptor AgonistsAmit Singh Adhikari, Annu Yadav, Soumen Pandit, et al.ACS Medicinal Chemistry Letters|December 17, 2025
Recent Developments in Cyclin-Dependent Kinase (CDK) PROTAC in Cancer TherapyArijit Nandi, Anwesha Das, M Rhia L Stone, et al.ACS Medicinal Chemistry Letters|April 16, 2025
A Tetrahydrobiopterin-Displacing Potent Neuronal Nitric Oxide Synthase Inhibitor with an Unprecedented Binding ModePathum M Weerawarna, Huiying Li, Athri D Rathnayake, et al.ACS Medicinal Chemistry Letters|April 16, 2025
End-to-End Backbone Cyclization Enhances Passive Permeability of bRo5 Oligomeric Depsipeptides with Nonlinear Size DependenceMadelaine P Thorpe, Corey R Hopkins, Jeffrey N JohnstonACS Medicinal Chemistry Letters|April 16, 2025
Novel Triazole-Substituted Imidazo[1,2-a]Pyrimidine Compounds as cGAS inhibitorsTaoqian Zhao, Steven H LiangPageof 438