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ACS Medicinal Chemistry Letters|June 6, 2014
Using medicinal chemistry to solve an old medical mysteryWilliam B Hinshaw, Louis D QuinACS Medicinal Chemistry Letters|June 6, 2014
Structure-Based Design of Irreversible Human KAT II Inhibitors: Discovery of New Potency-Enhancing InteractionsJamison B Tuttle, Marie Anderson, Bruce M Bechle, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Azepines and piperidines with dual norepinephrine dopamine uptake inhibition and antidepressant activityDean G Brown, Peter R Bernstein, Ye Wu, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Structural permutation of potent cytotoxin, polytheonamide B: discovery of cytotoxic Peptide with altered activityHiroaki Itoh, Masayuki InoueACS Medicinal Chemistry Letters|June 6, 2014
Identification of Tetrahydropyrido[4,3-d]pyrimidine Amides as a New Class of Orally Bioavailable TGR5 AgonistsDavid W Piotrowski, Kentaro Futatsugi, Joseph S Warmus, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Discovery and Biological Profiling of Potent and Selective mTOR Inhibitor GDC-0349Zhonghua Pei, Elizabeth Blackwood, Lichuan Liu, et al.ACS Medicinal Chemistry Letters|June 6, 2014
De novo prediction of p-glycoprotein-mediated efflux liability for druglike compoundsHakan Gunaydin, Matthew M Weiss, Yaxiong SunACS Medicinal Chemistry Letters|June 6, 2014
Biological evaluation of new largazole analogues: alteration of macrocyclic scaffold with click chemistryXianlin Li, Zhenchao Tu, Hua Li, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of DF-461, a Potent Squalene Synthase InhibitorMasanori Ichikawa, Masami Ohtsuka, Hitoshi Ohki, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of Clinical Candidate GSK1842799 As a Selective S1P1 Receptor Agonist (Prodrug) for Multiple SclerosisHongfeng Deng, Sylvie G Bernier, Elisabeth Doyle, et al.Pageof 438