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ACS Medicinal Chemistry Letters|March 18, 2026
Mechanistic Insights from Differences in the Aggregate Morphologies of Amphotericin B and Its Less Toxic Variant Am-2-19 (Turletricin)Luke Ting-Williams, Martin Stroet, Evelyne DeplazesACS Medicinal Chemistry Letters|March 18, 2026
Krüppel-like Factor 2 (KLF2) Inducing Agents and Their Therapeutic ApplicationsLingxin Meng, Steven H LiangACS Medicinal Chemistry Letters|March 18, 2026
Design, Synthesis, and Biological Evaluation of Novel 1H‑Imidazo[4,5-g]quinazoline-Based SOS1::KRASG12C Inhibitors in Colorectal Cancer CellsXu Huang, Jingkun Huang, Qianqian Hong, et al.ACS Medicinal Chemistry Letters|March 18, 2026
Synthesis of Novel USP1 Inhibitors and Their Uses in Treatment of USP1 Related DiseasesHaofeng Shi, Steven H LiangACS Medicinal Chemistry Letters|April 15, 2026
Structure-Based Drug Discovery of Non-SAM-Mimetic Bisubstrate Inhibitors against Nicotinamide N‑MethyltransferaseShuhei Yoshida, Noriyasu Kondo, Shota Uehara, et al.ACS Medicinal Chemistry Letters|April 15, 2026
Endocyclic Trisubstituted Hydroxylamine Isosteres of Basic Amines for ADME Modulation and Reduction of hERG ActivityIftikhar Khan, Asiri A Hettikankanamalage, Yizhi Cui, et al.ACS Medicinal Chemistry Letters|April 15, 2026
Evaluation of Oral PROTAC Guidelines: Efflux Ratio Outweighs Chameleonicity DescriptorsClaire Le Manach, Jenny Viklund, Karolina Kwapień, et al.ACS Medicinal Chemistry Letters|April 15, 2026
Identification of Natural-Product Inhibitors of the 2C‑Methyl‑d‑erythritol 4‑Phosphate PathwayEleonora Diamanti, Alaa Alhayek, Antoine Lacour, et al.ACS Medicinal Chemistry Letters|April 15, 2026
N‑Myristoyltransferase Inhibitors as a Potential Starting Point for the Development of Antischistosomal AgentsMareike Riedel, Collin Zimmer, Cécile Häberli, et al.ACS Medicinal Chemistry Letters|April 15, 2026
GHSR-Targeted PET Imaging ProbeRuihu Song, Steven H LiangPageof 441