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ACS Medicinal Chemistry Letters|August 20, 2026
Targeted Degradation of CDK2: A New Strategy for Overcoming Cyclin E‑Driven CancersAnna C Renner, Robert B Kargbo
ACS Medicinal Chemistry Letters|August 20, 2026
Nicotinamide-Based Covalent Inhibitors of tRNA (m1G37) Methyltransferase (TrmD) to Increase Antibacterial ActivityIsao Masuda, Simon D P Baugh, Kevin McClay, et al.
ACS Medicinal Chemistry Letters|August 20, 2026
Novel 6,5-Bicyclic Compounds as 5‑HT2A Receptor Agonists for Treating Depression, Anxiety, Substance Abuse, and HeadachesRam W Sabnis, Anika R Sabnis
ACS Medicinal Chemistry Letters|August 20, 2026
Synthetic Diastereomers of the Fungal Cycloheptapeptide Paraisariamide A Retain Ternatin-Like Biological ActivitySophia E Bonar, Daphne R Mattos, Takumi Arai, et al.
ACS Medicinal Chemistry Letters|August 20, 2026
Lipophilic Ligand Efficiency-Monitored Discovery of Potent, Achiral, and Bioavailable Apo-IDO1 InhibitorsWieslaw M Kazmierski, Nagaraju Miriyala, Martha De la Rosa, et al.
ACS Medicinal Chemistry Letters|August 20, 2026
Neutrophil Elastase-Responsive Linkers for Precision Antibody-Drug ConjugatesAnna C Renner, Robert B Kargbo
ACS Medicinal Chemistry Letters|August 20, 2026
Novel Compounds as SARS-CoV-2-Related 3C-Like Protease Inhibitors for Treating Coronavirus InfectionsRam W Sabnis
ACS Medicinal Chemistry Letters|August 20, 2026
Systems-Driven Identification and Experimental Validation of Actinomycetes-Derived Secondary Metabolites as Promising Antileishmanial Agents Targeting Leishmania donovani Methionyl-tRNA SynthetaseSatyendra Singh, Kirti Baghel, Preshita Bhalerao, et al.
ACS Medicinal Chemistry Letters|August 20, 2026
Peptidic Phosphonates as Irreversible Covalent Inhibitors of Plasmodium falciparum Serine Protease PfSUB1Armands Kazia, Elina Lidumniece, Chrislaine Withers-Martinez, et al.
ACS Medicinal Chemistry Letters|August 20, 2026
Structure-Guided Virtual Screening of Small Peptide Inhibitors Targeting PD-L1 for Cancer ImmunotherapyImani Roundtree, Rodney Valdivia, Angelo Altenor, et al.
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