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ACS Medicinal Chemistry Letters|December 17, 2025
Characterization of Novel Angiotensin-Converting Enzyme Inhibitory PeptidesCamila Innocente-Alves, Sara Luísa Sulzbach, Emerson Gonçalves Moreira, et al.
ACS Medicinal Chemistry Letters|November 19, 2025
Development of Purine and Pyrrolopyrimidine Scaffolds as Potent, Selective, and Brain Penetrant NUAK1 InhibitorsGregory G Aldred, Helen K Boffey, Henriette M G Willems, et al.
ACS Medicinal Chemistry Letters|November 19, 2025
Novel Bicyclic Compounds as TLR7 Agonists for Treating CancerRam W Sabnis
ACS Medicinal Chemistry Letters|November 19, 2025
Identification and Preliminary Characterization of a Novel Tasquinimod Analog that Unexpectedly Induces Mitotic Arrest by Alteration of Microtubule DynamicsGhassan M Abushaikha, Dewmi Rathnayake, Abdel Bayazid, et al.
ACS Medicinal Chemistry Letters|November 19, 2025
Academic-Industrial Collaboration in Synthesis with Real-Time Impact in Medicinal Chemistry: Discovery of Cystic Fibrosis C2 Corrector ABBV-602Eric A Voight, Wei Gong, David J Hardee, et al.
ACS Medicinal Chemistry Letters|November 19, 2025
Toward Precision Psychedelic Therapies: Chemical, Computational, and Neuromodulatory InnovationsAnna C Renner, Robert B Kargbo
ACS Medicinal Chemistry Letters|November 19, 2025
Discovery of Piperazine-Amide Derivatives as Highly Potent and Selective RET InhibitorsPenghao Luo, Panpan Zhang, Yingxuan Xu, et al.
ACS Medicinal Chemistry Letters|November 19, 2025
Structure-Based Ligandability Exploration of a G‑Quadruplex-Forming Sequence from the Pseudomonas aeruginosa GenomeMartina Fiabane, Chiara Platella, Fabiana Diaco, et al.
ACS Medicinal Chemistry Letters|November 19, 2025
Novel Psilocin Derivatives as Serotonergic Psychedelic Agents for Treating CNS DisordersRam W Sabnis
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