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Biochemical Pharmacology|January 29, 2025
A novel amino-pyrimidine inhibitor suppresses tumor growth via microtubule destabilization and Bmi-1 down-regulationLijie Gao, Jiawei Liu, Rui Zhang, et al.
Biochemical Pharmacology|January 23, 2025
Targeting GSDMD JX06 inhibits PANoptosis and multiple organ injuryShiyi Chen, Guo-Dong Wu, Tongfu Li, et al.
Biochemical Pharmacology|January 12, 2025
Pym-18a, a novel pyrimidine derivative ameliorates glucocorticoid induced osteoblast apoptosis and promotes osteogenesis via autophagy and PINK 1/Parkin mediated mitophagy inductionSonu Khanka, Sumit K Rastogi, Krishna Bhan Singh, et al.
Biochemical Pharmacology|January 20, 2025
Mast cell activation induced by tamoxifen citrate via MRGPRX2 plays a potential adverse role in breast cancer treatmentJiapan Gao, Xinyue Su, Yuxiu Zhang, et al.
Biochemical Pharmacology|January 12, 2025
5,7-Dihydroxy-4-Methylcoumarin enhances osteogenesis and ameliorates osteoporosis via the AKT1 pathwayHan Diao, Houzhi Yang, Bin Yu, et al.
Biochemical Pharmacology|January 10, 2025
JOSD2 promotes breast cancer metastasis by deubiquitinating and stabilizing SMAD4Jiamin Du, Jiao Wang, Fujing Ge, et al.
Biochemical Pharmacology|January 17, 2025
DEC1 deficiency promotes osteoclastic activity by augmenting NFATc1 signaling via transactivation and the Ca2+/calcineurin pathwayHaobin Wang, Yu Guan, Lan Lin, et al.
Biochemical Pharmacology|January 17, 2025
First generation vanadium-based PTEN inhibitors: Comparative study in vitro and in vivo and identification of a novel mechanism of actionKyriaki Premeti, Dimitra Tsipa, Antonios E Nadalis, et al.
Biochemical Pharmacology|January 17, 2025
PSMC2 promotes resistance against temozolomide in glioblastoma via suppressing JNK-mediated autophagic cell deathPritam Kumar Roy, K Deepak, Chandan Kanta Das, et al.
Biochemical Pharmacology|December 6, 2024
The TFEB activator clomiphene citrate ameliorates lipid metabolic syndrome pathology by activating lipophagy and lipolysisLu Li, Jieru Lin, Chunhuan Huang, et al.
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