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Bioorganic & Medicinal Chemistry|June 29, 2010
2-acylamino-4,6-diphenylpyridine derivatives as novel GPR54 antagonists with good brain exposure and in vivo efficacy for plasma LH level in male ratsToshitake Kobayashi, Satoshi Sasaki, Naoki Tomita, et al.
Bioorganic & Medicinal Chemistry|June 18, 2010
A novel and one-pot synthesis of new 1-tosyl pyrrol-2-one derivatives and analysis of carbonic anhydrase inhibitory potenciesCemalettin Alp, Deniz Ekinci, Mehmet Serdar Gültekin, et al.
Bioorganic & Medicinal Chemistry|June 26, 2010
Design, synthesis, and docking of highly hypolipidemic agents: Schizosaccharomyces pombe as a new model for evaluating alpha-asarone-based HMG-CoA reductase inhibitorsNancy Argüelles, Eugenia Sánchez-Sandoval, Aarón Mendieta, et al.
Bioorganic & Medicinal Chemistry|June 26, 2010
Design, synthesis, and biological evaluation of novel coxsackievirus B3 inhibitorsMichal Sála, Armando M De Palma, Hubert Hrebabecký, et al.
Bioorganic & Medicinal Chemistry|July 9, 2010
Efficient synthesis of Hsp90 inhibitor dimers as potential antitumor agentsHironori Sekiguchi, Kazuhiro Muranaka, Akiko Osada, et al.
Bioorganic & Medicinal Chemistry|July 21, 2010
Synthesis of aryl-heteroaryl ureas (AHUs) based on 4-aminoquinoline and their evaluation against the insulin-like growth factor receptor (IGF-1R)William Engen, Terrence E O'Brien, Brendan Kelly, et al.
Bioorganic & Medicinal Chemistry|July 28, 2010
In vitro ADMET and physicochemical investigations of poly-N-methylated peptides designed to inhibit Abeta aggregationPartha Pratim Bose, Urmimala Chatterjee, Ina Hubatsch, et al.
Bioorganic & Medicinal Chemistry|July 28, 2010
Synthesis and T-type calcium channel blocking activity of novel diphenylpiperazine compounds, and evaluation of in vivo analgesic activityYoo Lim Kam, Hee-Kyung Rhee, Hyewhon Rhim, et al.
Bioorganic & Medicinal Chemistry|August 10, 2010
A class of novel carboline intercalators: Their synthesis, in vitro anti-proliferation, in vivo anti-tumor action, and 3D QSAR analysisJianhui Wu, Chunyu Li, Ming Zhao, et al.
Bioorganic & Medicinal Chemistry|August 19, 2010
FRET-based sensors for the human M1-, M3-, and M5-acetylcholine receptorsNicole Ziegler, Julia Bätz, Ulrike Zabel, et al.
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