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Bioorganic & Medicinal Chemistry Letters|September 24, 2018
Synthesis of novel mono and bis nitric oxide donors with high cytocompatibility and release activityTanya Sahyoun, Caroline Gaucher, Yi Zhou, et al.Bioorganic & Medicinal Chemistry Letters|September 24, 2018
Optimization of the efflux ratio and permeability of covalent irreversible BTK inhibitorsHui Qiu, Lesley Liu-Bujalski, Richard D Caldwell, et al.Bioorganic & Medicinal Chemistry Letters|May 20, 2018
A small diversity library of α-methyl amide analogs of sulindac for probing anticancer structure-activity relationshipsBini Mathew, Timothy S Snowden, Michele C Connelly, et al.Bioorganic & Medicinal Chemistry Letters|May 20, 2018
Discovery of novel N-hydroxy-2-arylisoindoline-4-carboxamides as potent and selective inhibitors of HDAC11Matthew W Martin, Jennifer Y Lee, David R Lancia, et al.Bioorganic & Medicinal Chemistry Letters|July 5, 2018
Design, synthesis, X-ray studies, and biological evaluation of novel BACE1 inhibitors with bicyclic isoxazoline carboxamides as the P3 ligandArun K Ghosh, Koena Ghosh, Margherita Brindisi, et al.Bioorganic & Medicinal Chemistry Letters|July 15, 2018
Polyamine-containing etoposide derivatives as poisons of human type II topoisomerases: Differential effects on topoisomerase IIα and IIβAlexandria A Oviatt, Jissy A Kuriappan, Elirosa Minniti, et al.Bioorganic & Medicinal Chemistry Letters|July 15, 2018
The improvement of lysosome targetability with oligoethyleneoxy chains linked benzo[a]phenoxazineWei-Jin Zhu, Jin-Yun Niu, Ru Sun, et al.Bioorganic & Medicinal Chemistry Letters|June 4, 2018
'Tethering' fragment-based drug discovery to identify inhibitors of the essential respiratory membrane protein type II NADH dehydrogenaseAdam Heikal, Yoshio Nakatani, Wanting Jiao, et al.Bioorganic & Medicinal Chemistry Letters|June 4, 2018
Structural basis for the selective inhibition of activated thrombin-activatable fibrinolysis inhibitor (TAFIa) by a selenium-containing inhibitor with chloro-aminopyridine as a basic groupToshimasa Itoh, Nobuko Yoshimoto, Yoshinari Hirano, et al.Bioorganic & Medicinal Chemistry Letters|July 24, 2018
Generation of methylated violapyrones with improved anti-influenza A virus activity by heterologous expression of a type III PKS gene in a marine Streptomyces strainLukuan Hou, Shuyao Wang, Huiming Huang, et al.Pageof 2,632