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Bioorganic & Medicinal Chemistry Letters|May 20, 2017
Challenges in the development of an M4 PAM preclinical candidate: The discovery, SAR, and in vivo characterization of a series of 3-aminoazetidine-derived amidesJames C Tarr, Michael R Wood, Meredith J Noetzel, et al.Bioorganic & Medicinal Chemistry Letters|May 26, 2017
Switching subtype-selectivity: Fragment replacement strategy affords novel class of peroxisome proliferator-activated receptor α/δ (PPARα/δ) dual agonistsRyuta Shioi, Shogo Okazaki, Tomomi Noguchi-Yachide, et al.Bioorganic & Medicinal Chemistry Letters|May 26, 2017
Discovery of novel cyclic peptide inhibitors of dengue virus NS2B-NS3 protease with antiviral activityYouhei Takagi, Kouhei Matsui, Haruaki Nobori, et al.Bioorganic & Medicinal Chemistry Letters|May 2, 2017
Nucleobase azide-ethynylribose click chemistry contributes to stabilizing oligonucleotide duplexes and stem-loop structuresYoshiaki Kitamura, Ryo Asakura, Koki Terazawa, et al.Bioorganic & Medicinal Chemistry Letters|May 27, 2018
Structure-activity relationship of uridine-based nucleoside phosphoramidate prodrugs for inhibition of dengue virus RNA-dependent RNA polymeraseGang Wang, Siew Pheng Lim, Yen-Liang Chen, et al.Bioorganic & Medicinal Chemistry Letters|May 10, 2018
Expedient on-resin synthesis of peptidic benzimidazolesMichael J Bird, Anthony P Silvestri, Philip E DawsonBioorganic & Medicinal Chemistry Letters|July 10, 2017
Novel derivatives of deoxycholic acid bearing aliphatic or cyclic diamine moieties at the C-3 position: Synthesis and evaluation of anti-proliferative activityIrina I Popadyuk, Andrey V Markov, Valeriya O Babich, et al.Bioorganic & Medicinal Chemistry Letters|July 11, 2017
Structure-based optimization and synthesis of antiviral drug Arbidol analogues with significantly improved affinity to influenza hemagglutininZoë V F Wright, Nicholas C Wu, Rameshwar U Kadam, et al.Bioorganic & Medicinal Chemistry Letters|May 7, 2018
Synthesis and activity of di- or trisubstituted N-(phenoxyalkyl)- or N-{2-[2-(phenoxy)ethoxy]ethyl}piperazine derivatives on the central nervous systemKatarzyna Pańczyk, Karolina Pytka, Magdalena Jakubczyk, et al.Bioorganic & Medicinal Chemistry Letters|May 7, 2018
Determination of absolute configuration and binding efficacy of benzimidazole-based FabI inhibitors through the support of electronic circular dichroism and MM-GBSA techniquesJinhong Ren, Tina L Mistry, Pin-Chih Su, et al.Pageof 2,632