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Bioorganic & Medicinal Chemistry Letters|March 19, 2016
Induction of apoptosis and differentiation by atractylenolide-1 isolated from Atractylodes macrocephala in human leukemia cellsHuey-Lan Huang, Tzu-Wen Lin, Yu-Ling Huang, et al.
Bioorganic & Medicinal Chemistry Letters|March 19, 2016
Lead optimization of the VU0486321 series of mGlu1 PAMs. Part 3. Engineering plasma stability by discovery and optimization of isoindolinone analogsPedro M Garcia-Barrantes, Hyekyung P Cho, Anna L Blobaum, et al.
Bioorganic & Medicinal Chemistry Letters|March 19, 2016
New pentasubstituted pyrrole hybrid atorvastatin-quinoline derivatives with antiplasmodial activityRita C C Carvalho, Wagner A Martins, Tayara P Silva, et al.
Bioorganic & Medicinal Chemistry Letters|March 19, 2016
N-Alkylpyrido[1',2':1,5]pyrazolo-[4,3-d]pyrimidin-4-amines: A new series of negative allosteric modulators of mGlu1/5 with CNS exposure in rodentsAndrew S Felts, Alice L Rodriguez, Ryan D Morrison, et al.
Bioorganic & Medicinal Chemistry Letters|March 21, 2016
Design, synthesis and structure activity relationship of potent pan-PIM kinase inhibitors derived from the pyridyl carboxamide scaffoldGisele A Nishiguchi, Matthew T Burger, Wooseok Han, et al.
Bioorganic & Medicinal Chemistry Letters|March 21, 2016
Minimum structural requirements for cell membrane leakage-mediated anti-MRSA activity of macrocyclic bis(bibenzyl)sKana Fujii, Daichi Morita, Kenji Onoda, et al.
Bioorganic & Medicinal Chemistry Letters|March 22, 2016
Piperidine derivatives as nonprostanoid IP receptor agonistsRyoji Hayashi, Hideki Sakagami, Masakazu Koiwa, et al.
Bioorganic & Medicinal Chemistry Letters|March 22, 2016
Discovery of a series of 8-(2,3-dihydro-1,4-benzoxazin-4-ylmethyl)-2-morpholino-4-oxo-chromene-6-carboxamides as PI3Kβ/δ inhibitors for the treatment of PTEN-deficient tumoursBernard Barlaam, Sabina Cosulich, Sébastien Degorce, et al.
Bioorganic & Medicinal Chemistry Letters|April 16, 2016
One-pot synthesis of 1,4-dihydroxy-2-((E)-1-hydroxy-4-phenylbut-3-enyl)anthracene-9,10-diones as novel shikonin analogs and evaluation of their antiproliferative activitiesLi-Ming Zhao, Feng-Xia Cao, Hai-Shan Jin, et al.
Bioorganic & Medicinal Chemistry Letters|April 16, 2016
Discovery of triazolopyridine GS-458967, a late sodium current inhibitor (Late INai) of the cardiac NaV 1.5 channel with improved efficacy and potency relative to ranolazineDmitry O Koltun, Eric Q Parkhill, Elfatih Elzein, et al.
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