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Bioorganic & Medicinal Chemistry Letters|October 10, 2020
Hit-to-lead optimization and discovery of a potent, and orally bioavailable G protein coupled receptor kinase 2 (GRK2) inhibitorGuozhang Xu, Michael D Gaul, Zhijie Liu, et al.Bioorganic & Medicinal Chemistry Letters|October 10, 2020
Computational modeling and target synthesis of monomethoxy-substituted o-diphenylisoxazoles with unexpectedly high antimitotic microtubule destabilizing activityVictor S Stroylov, Igor V Svitanko, Anna S Maksimenko, et al.Bioorganic & Medicinal Chemistry Letters|October 10, 2020
Pharmacophore modeling, design, and synthesis of potent antihypertensives, oxazolo/thiazolo-[3,2-a]-pyrimidin-3(2H)-one, and 1,5-dihydroimidazo-[1,2-a]-pyrimidin-3(2H)-one derivatives: A pilot trialManoj Keshari, Riaz A Khan, Habibullah Khalilullah, et al.Bioorganic & Medicinal Chemistry Letters|July 8, 2021
Novel triazole-sulfonamide bearing pyrimidine moieties with carbonic anhydrase inhibitory action: Design, synthesis, computational and enzyme inhibition studiesShoaib Manzoor, Andrea Petreni, Md Kausar Raza, et al.Bioorganic & Medicinal Chemistry Letters|July 5, 2022
Discovery of novel polyamide-pyrrolobenzodiazepine hybrids for antibody-drug conjugatesJoshua D Thomas, Aleksandr V Yurkovetskiy, Mao Yin, et al.Bioorganic & Medicinal Chemistry Letters|June 2, 2022
Eukaryotic artificial ON-riboswitches that respond efficiently to mid-sized short peptidesHajime Takahashi, Ryo Okubo, Atsushi OgawaBioorganic & Medicinal Chemistry Letters|June 1, 2022
Preparation of a multifunctional photoactivated prodrug on a streptavidin scaffold bearing a DNA aptamerYuto Motohashi, Tatsuya Nishihara, Kazuhito TanabeBioorganic & Medicinal Chemistry Letters|June 14, 2022
Multigram-scale total synthesis of (±)-ambreinolide by a diastereoselective polyene cyclizationPaul Wienecke, Helmar Görls, Hans-Dieter ArndtBioorganic & Medicinal Chemistry Letters|June 14, 2022
Synthesis and evaluation of Diaza-Crown Ether-Backboned chelator containing hydroxamate groups for Zr-89 chelation chemistryShuyuan Zhang, Haixing Wang, Siyuan Ren, et al.Bioorganic & Medicinal Chemistry Letters|June 20, 2022
Design, synthesis and biological evaluation of novel aminopropylcarboxamide derivatives as sigma ligandsDaniele Zampieri, Sara Fortuna, Maurizio Romano, et al.Pageof 2,631